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Hindi International Journal of Cardiovascular ResearchISSN: 2324-8602
Nasri Alotti Author
Subjects of specialization
Affiliation
Mitral regurgitation, Mitral valve repair
Department of Cardiac Surgery, Zala County Teaching Hospital & P
Biography
Department of Cardiac Surgery, Zala County Teaching Hospital & Pécs University of Science, Hungary published an article on Early Results of a Novel Mitral Valve Repair Procedure: The Interpapillary Polytetrafluoroethylene Bridge Formation.
Publications
Research Article Open Access
Denosumab could be a Potential Inhibitor of Valvular Interstitial Cells Calcification in vitro
Author(s): Daniel Alejandro Lerman, Sai Prasad and Nasri Alotti
Denosumab could be a Potential Inhibitor of Valvular Interstitial Cells Calcification in vitro
Objective: Denosumab is a fully human monoclonal antibody and novel antiresorptive agent that works by binding receptor activator of nuclear factor kappa-β ligand (RANKL) and inhibiting the signaling cascade that causes osteoclast maturation, activity, and survival. We aimed to elucidate the effect of Denosumab in the process of spontaneous and induced calcification in an in vitro porcine valvular interstitial cells (VICs) model.
Materials and Methods: VICs were extracted from fresh porcine hea... view more»
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