Onunekwu O. Charles Author

Special Issue Article Open Access

POST TRAUMATIC STRESS DISORDER AND THE TOXICOLOGY OF CANNABIS SATIVA

Author(s):

Onunekwu O. Charles, 2Yusuf, N. Omeh. 3Bruno O. Onyemegbulem, 4J.C Aguiyi 
 1,2Michael Okpara 

Many young men, women and even the elderly are addicted to Cannabis intake abuse despite its predictable toxicological consequences. In this paper we studied the toxic effects of oral administration of methanol extract of cannabis sativa seeds using total of forty male Wistar Rats. Animals randomized were into five groups (n=8rats) of approximately equal weight. Group 1 received 100mg/kg of the of the extract, group 2 received 200mg/kg of the extract, group 3 received 300mg/kg dosage of the extract, group 4 received 2ml of olive oil and group 5 received distilled water for 14 days. Result for AST was significantly (p<0.05) higher in groups 2 (57.00±13.00IU/L) and 3 (59.33±10.53IU/L), compared with normal control group 5 (31.33±1.53 IU/L). Significantly (p<0.05... view more»

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