Journal of Regenerative MedicineISSN: 2325-9620

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Patrick J Atkinson Author

Subjects of specialization
Neuroscience, Psychology

Affiliation
Department of Otolaryngology, School of Medicine, Stanford University, Stanford, CA, USA

Biography

Patrick J Atkinson graduated with a degree in Science, majoring in Neuroscience and Psychology, with honours in Otolaryngology from the University of Melbourne in 2007. Two years were then spent at the University of Iowa as a research assistant prior to moving back to Australia to complete my PhD at the Bionics Institute and the University of Melbourne. My specific research interests include the use of novel techniques to promote neural survival and the regeneration of sensory cells within the nervous system.


Publications

Research Article Subscription

Regeneration of Cochlear Hair Cells with Atoh1 Gene Therapy after Noise-Induced Hearing Loss

Author(s):

Andrew K Wise, Brianna O Flynn, Patrick J Atkinson, James B Fallon, Madeline Nicholson and Rachael T Richardson

Background: Degeneration of hair cells in the mammalian cochlea results in irreversible hearing loss with no current treatment options to regain lost hair cell function. The Atoh1 gene is necessary for hair cell development and recent research has shown that Atoh1 gene therapy promotes new hair cell formation and hearing restoration in adult rodent deafness models.

Objective: The aim of this study was to examine new hair cell formation via Atoh1 gene therapy in noise-deafened adult guinea pigs. Methods: Guinea pigs were deafened by noise exposure (130 dB, 11-13 kHz, 2 hours). After two weeks, the left cochleae were injected wit... view moreĀ»

DOI: 10.4172/2325-9620.1000121

Abstract HTML PDF



Social Media


Google Scholars / Researchers Sites

GET THE APP