Patrick J Atkinson Author
Subjects of specialization
Affiliation
Neuroscience, Psychology
Department of Otolaryngology, School of Medicine, Stanford University, Stanford, CA, USA
Patrick J Atkinson graduated with a degree in Science, majoring in Neuroscience and Psychology, with honours in Otolaryngology from the University of Melbourne in 2007. Two years were then spent at the University of Iowa as a research assistant prior to moving back to Australia to complete my PhD at the Bionics Institute and the University of Melbourne. My specific research interests include the use of novel techniques to promote neural survival and the regeneration of sensory cells within the nervous system.
Research Article Subscription
Author(s): Andrew K Wise, Brianna O Flynn, Patrick J Atkinson, James B Fallon, Madeline Nicholson and Rachael T Richardson
Background: Degeneration of hair cells in the mammalian cochlea results in irreversible hearing loss with no current treatment options to regain lost hair cell function. The Atoh1 gene is necessary for hair cell development and recent research has shown that Atoh1 gene therapy promotes new hair cell formation and hearing restoration in adult rodent deafness models.
Objective: The aim of this study was to examine new hair cell formation via Atoh1 gene therapy in noise-deafened adult guinea pigs. Methods: Guinea pigs were deafened by noise exposure (130 dB, 11-13 kHz, 2 hours). After two weeks, the left cochleae were injected wit... view moreĀ»