S B Usmani Author

Short Communication Open Access

Bioassay-Directed Isolation of Hypotensive Alkaloids from Holarrhena Pubescens

Author(s):

K Aftab*, S B Usmani, S Begum and B S Siddiqui

Holarrhena pubescens contains a put to the family Apocynacea, commonly known as “kurchi” is significantly rumored in ordinary pharmaceutical as a remedy for amoebic loose bowels and other intestinal affliction. Bioassay-directed fractionation by chromatographic techniques the ethanolic remove of Holarrhena pubescens brought approximately inside the imprisonment of steroidal alkaloids i.e. Holamide and Pubscinine. Holamide showed up a three proton doublet at 1.45 (J=6.56 Hz) and two AB duplicates at 3.17 and 3.00 each for on proton (J=12.06 Hz) within the 1H NMR extend prescribed that it encompasses a put to cocaine course of action of alkaloid (A lesson of compound with the steroid center and a five people heterocyclic ring with nitrogen).

In separate Pubscinine sh... view more»

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