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Hindi Journal of Regenerative MedicineISSN: 2325-9620
Sepideh Heydarkhan-Hagvall Author
Subjects of specialization
Affiliation
Cardiothoracic Surgery, Tissue Engineering
Department of Cardiothoracic Surgery David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, 62-151 CHS, Los Angeles, CA 90095-1741, USA
Biography
Sepideh Heydarkhan Hagvall is an Assistant Adjunct Professor in David Geffen School of Medicine at UCLA. He is working at Department of Surgery in Division of Cardiothoracic BOX 9517741, 62-151 CHS Los Angeles, CA 90095-1741. His Research Interest are Cardiothoracic Surgery , Tissue Engineering.
Publications
Research Article Subscription
Dedifferentiated Adipocytes Improve Heart Function Post-Myocardial Infarction
Author(s): Eric J Tsang, Maria C Jordan, Kenneth P Roos, Jessica M Gluck, Medet Jumabay, Kristina I Boström, Richard J Shemin and Sepideh Heydarkhan-Hagvall
Background:The development of pluripotent stem cell-based strategies for regenerative medicine offers hope of one day having a limitless source of therapeutic cells for the repairing of damaged cardiac tissue resulting from myocardial infarction (MI). Dedifferentiated adipose cells (DFAT) have recently gained attention in this regard for their in vitro and in vivo ability to express vascular and cardiac-specific markers. To date, there is limited knowledge with respect to their capacity to improve cardiac function and contractility when introduced into the myocardium after the onset of MI. To that end, this study investigated the in vivo potential of intramyocardially injected mouse DFAT (mDFAT) cells to differentiate towards cardiovascular lineages and enhance cardiac ... view more»
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