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Hindi Analgesia & Resuscitation : Current ResearchISSN: 2324-903X
Shiro Mishima Author
Subjects of specialization
Affiliation
Emergency Medicine, Critical Care Medicine
Department of Emergency and Critical Care Medicine, Tokyo Medical University Hospital, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, Japan
Biography
He is affiliated to Department of Emergency and Critical Care Medicine, Tokyo Medical University Hospital, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, Japan. He is a recipient of many awards and grants for his valuable contributions and discoveries in major area of subject research.
Publications
Research Article Subscription
Bifidobacterium longum BB536 and Changes in Septicemia Markers Associated with Antibiotic Use in Critically Ill Patients
Author(s): Takao Arai, Shiro Mishima, Shoichi Ohta, Tetsuo Yukioka and Tetsuya Matsumoto
Objective: Probiotics exert beneficial effects on gastrointestinal microflora, but these effects may be counteracted by antibiotics, particularly when used in critically ill patients. The aim of this study was to examine the effects of probiotics in association with antibiotics on septicemia markers.
Methods: In total, 64 critically ill patients were randomized to receive conventional therapy alone (control group) or with a transluminal preparation containing Bifidobacterium longum BB536 (probiotic group). Patients were retrospectively divided into two subgroups depending on whether they received antibiotic therapy during the study period. Outcome measures included fecal bifidobacteria numbers and serum concentrations of procalcitonin and interleukin 6.
Results: Af... view more»
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