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Hindi International Journal of Mental Health & PsychiatryISSN: 2471-4372
Simon Chiu Author
Subjects of specialization
Affiliation
cAMP; Phosphodiestease; Serotonin; Zembrin extract; Sceletium tortuosum; Alzheimer?s disease
Lawson Health Research Institute, London, Ontario, N6A 4V2, Canada
Biography
Mr. Chiu is a Principal and Head of Accounts Payable in the Ares Global Services Group. Prior to joining Ares in 2017, Mr. Chiu was the Global Process Owner of Accounts Payable at Bloomberg L.P. in New York. Previously, Mr. Chiu was a Director at Credit Suisse, where he was responsible for global procure-to-pay operations and travel and expense management. Mr. Chiu holds a B.S. from the University of Hartford in Accounting.
Publications
Review Article Subscription
Exploring Zembrin Extract Derived from South African Plant, Sceletium tortuosum in Targeting cAMP-driven Phosphodiesterase (PDE) Signaling in Alzheimer’s Disease: Synthesis of Evidence
Author(s): Simon Chiu, Hana Raheb, Kristen Terpstra, JoshVaughan, Michel Farina-Woodbury, Yves Bureau, Zack Cernovsky, Jirui Hou, John Copen, Mariwan Husni, Vladimir Badmeav, Ana Hategan, Mujeeb Shad, Zach Suntras, Nigel Gericke
Recently with the changing landscape of the aging population and the increase in incidence of Alzheimer’s disease (AD), there has been marked interest to develop strategies to prevent, delay and modify AD. We review the diverse lines of evidence in support of the emerging role of cAMP-mediated Phosphodiesterase (PDE) signalling with respect to aging, inflammation and depression. In view of the link of PDE to Epigenetic complex, targeting PDE through designing modulators and inhibitors of PDE may represent a novel approach in AD therapeutics. We... view more»
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