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Srojidinova NZ Author
Subjects of specialization
Affiliation
Essential hypertension
Department of Arterial Hypertension and Molecular Genetics Research, Republican specialized medical center of cardiology, Tashkent, Uzbekistan
Biography
Srojidinova NZ, Department of Arterial Hypertension and Molecular Genetics Research, Republican specialized medical center of cardiology, Tashkent, Uzbekistan. His Research Interest is Essential hypertension He has published several research articles in many reputed journal.
Publications
Research Article Open Access
CYPs Genotyping, Essential Hypertension and Frequencies of Mutant Alleles in an Uzbek Population
Author(s): Nagay AV, Khamidullayeva GA, Srojidinova NZ and Kurbanov RD
Background and Objectives: Each patient has a combination of the genes bound to cardiovascular illnesses. The aim of our study was to determine the features of the distribution of genes associated with hypertension. In this paper we have described the 4 polymorphic loci distinctive susceptibility to hypertension. There are 4 polymorphisms of genes in nuclear DNA (CYP2C19 *2 CYP3A5, CYP2C9-3 and CYP2C9-2).
Materials and Methods: The study included 109 Uzbek men (mean age 48 ± 11 years) with untreated EH of stage 1-2 and 82 normotensive males.
Results: Distribution of allele frequency of, CYP2C19 *2 CYP3A5, CYP2C9-3 and CYP2C9-2 genes was similar with Saudi Arabian, Afro-American, Spain and European American population ... view more»
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