Journal of Chromatography Research

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Suzan Elif Akuuml;n Author

Subjects of specialization
Biochemistry

Affiliation
Department of biochemistry, Faculty of science at Ege University, Turkey

Biography

Suzan Elif Akün is undergraduated Biochemistry student at the age of 24 years from Ege University, Turkey. She had a speech about treatment of Alzheimer disease at ?zmir Biomedicine and Genome Center open days. Also, she has attended many congress with academic posters. She had an internship on Colorectal Cancer and Biosensory researches.


Publications

Short Communication Open Access

The evaluation of CYP2D6, CYP2C9 and CYP2C19 polymorphisms by genosensor for personalized medicine in psychiatry patients

Author(s):

Suzan Elif Akün

The cytochrome P450 proteins are drug-metabolizing enzymes that involves in many catalytic reactions. Genetic variability (polymorphism) in these enzymes may influence a patient’s response to commonly prescribed drug classes, including beta blockers and antidepressants. The aim of this study is to evaluate the CYP2D6, CYP2C9, CYP2C19 polymorphisms of shizophrenic and bipolar patients in the therapeutic response that allow the treatment to be individualized. This study was carried out on patients who attended the Cukurova University Psychiatric Unit with a diagnosis of schizophrenia and bipolar disorder involved in our study. There are several drugs should dose adjustment, reduce the toxicity and increase the effects for P450 enzymes. Genetic polymorphism of hum... view moreĀ»

Abstract PDF



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