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Hindi Analgesia & Resuscitation : Current ResearchISSN: 2324-903X
Tetsuya Matsumoto Author
Subjects of specialization
Affiliation
Microbiology
Department of Microbiology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo, Japan.
Biography
Graduation of Nagasaki University Medical School, Japan and trained in the Department of Second Internal Medicine of the University. Graduation of post graduated course of Nagasaki University Medical School. Research fellow at Channing Laboratory, Harvard Medical School, Boston, USA. Associate professor, Department of Microbiology, Toho University School of Medicine, Tokyo. Chief Professor of Department of Microbiology, Tokyo Medical University, Tokyo. Chief Professor of Department of Infectious Diseases, International University of Health and Welfare, Narita.
Publications
Research Article Subscription
Bifidobacterium longum BB536 and Changes in Septicemia Markers Associated with Antibiotic Use in Critically Ill Patients
Author(s): Takao Arai, Shiro Mishima, Shoichi Ohta, Tetsuo Yukioka and Tetsuya Matsumoto
Objective: Probiotics exert beneficial effects on gastrointestinal microflora, but these effects may be counteracted by antibiotics, particularly when used in critically ill patients. The aim of this study was to examine the effects of probiotics in association with antibiotics on septicemia markers.
Methods: In total, 64 critically ill patients were randomized to receive conventional therapy alone (control group) or with a transluminal preparation containing Bifidobacterium longum BB536 (probiotic group). Patients were retrospectively divided into two subgroups depending on whether they received antibiotic therapy during the study period. Outcome measures included fecal bifidobacteria numbers and serum concentrations of procalcitonin and interleukin 6.
Results: Af... view more»
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