the nervous system acts as a crucial part of the cancer microenvironme Author

Short Communication Open Access

The constitution of the cancer tissues

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The growth of cancers depends on the formation of blood vessels that provide the supply of nutrients and oxygen and the nervous system acts as a crucial part of the cancer microenvironment. Angiogenesis and vasculogenesis are essential during cancer progression. Recently, several studies have reported that glioblastoma stem cells are able to giv

The growth of cancers depends on the formation of blood vessels that provide the supply of nutrients and oxygen and the nervous system acts as a crucial part of cancer microenvironment. The angiogenesis and vasculogenesis are essential during cancer progression. Recently, several studies have reported that glioblastoma stem cells are able to give rise to tumor vascular endothelial cells (ECs) and vascular pericytes for tumor vascularization. However, there is no evidence to show that the tumor stem cells from other kinds of tumors including carcinoma produce endothelial cells to constitute the functional blood vessels in cancer. In addition, recent evidences have demonstrated that the stimulation of both cancer growth and metastasis by members of nervous system such as neurons. How the ... view more»

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