Tiago Lima Sampaio | Author | SciTechnol

Tiago Lima Sampaio Author

tiagosampaio91@gmail.com 5585988574473 | 558598857447

Subjects of specialization
Single nucleotide polymorphisms

Affiliation
Department of Clinical and Toxicological Analysis, Federal University of Cear

Biography

Tiago Lima Sampaio Department of Clinical and Toxicological Analysis, Federal University of Ceará, Brazil. His publications include: Martín-Campos JM, Ruiz-Nogales S, Ibarretxe D, Ortega E, Sánchez-Pujol E, et al. (2020) Polygenic markers in patients diagnosed of autosomal dominant hypercholesterolemia in catalonia: distribution of weighted LDL-C-raising snp scores and refinement of variant selection. Biomedicines 8: 353.

Publications

Editorial Open Access

The Cardiovascular Risk Research in Alzheimerâ€™s Disease and Other Neurodegenerative Diseases

Author(s):

Tiago Lima Sampaio and Erlânia Alves de Siqueira

The occurrence of chronic and neurodegenerative diseases is epidemiologically important in elderly population, including Alzheimer’s Disease (AD). Risk factors such as diabetes, obesity, hypertension, Cardiovascular Diseases (CVD), hyperlipidemia, hyperhomocysteinemia, and smoking can lead to Cerebrovascular Diseases (CBVD). The neurodegeneration is consequence of cumulative macro and microcirculatory damage, corroborating to increase in systolic pressure, neuroinflammation, oxidative stress, and excitotoxicity. There are some intersections between AD and CVD. For example, ε4 allele of the Apolipoprotein E (APOE) gene is a risk; low plasma levels of ApoE protein favor the risk of AD, regardless of the APOE genotype. Furthermore, the insulin resistance causes atrophy of the... view more»

DOI: 10.37532/icrj.2021.10(1).430

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