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Yabar CA Author
Subjects of specialization
Affiliation
HIV, AIDS
HIV / AIDS Laboratory Instituto Nacional de Salud, Peru
Biography
Dr. Carlos Augusto Yabar is affiliated to AIDS / HIV laboratory of Instituto Nacional de Salud of Peru. Dr. Carlos Augusto Yabar is currently providing services as Molecular Biologist at HIV genotyping area, Dr. Carlos Augusto Yabar has authored multiple national and international peer-reviewed scientific papers and presented works at many national and International conferences about AIDS and other infectious diseases. Dr. Carlos Augusto Yabar contributions have acclaimed recognition from honourable subject experts around the world.
Publications
Research Article Open Access
Multiple Resistance and Unusual Mutations from HIV-1 Infecting Peruvian Patients with Highly Active Antiretroviral Therapy
Author(s): Yabar CA, Vilcarino G, Yaya M, Espetia S, Acuña M, Mamami E, Santos D, Romero S and Bustamante FC
We have analyzed the molecular resistance profile of HIV infecting Peruvian individuals during the first three years that genotyping test was implemented free of charge. According our results, from 297 patients 80% of them were resistant to one or more antiretroviral (ART). M184V was the most frequent resistant mutation (30% for children and 26% for adults). Resistant profile revealed that children showed more resistance to 3TC / FTC (78%), while in adults it was EFV / NVP (50%). Pan-sensitive patients showed similar virological and immunological failure as those of resistant patients. We have also identified six patients showing Pan-resistance, including a 7-year-old subject. Additional sequence analysis revealed two cases of hypermutation with multiple sto... view more»
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