Yonatan Mesfin Author

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Stem Cell Biology and its Role in Regenerative Medicine: A Concept Shaping the Future of Medicine

Author(s):

Melkamu Bezie, Yonatan Mesfin and Habtamu Biyazen

Stem cells are special type of cells that have unique capacity to renew themselves and differentiate to give rise to specialized cell types for many tissues. Hence, they are the principal cells of all cell types. Stem cells can be embryonic, fetal, and adult or somatic types. Cells can be reprogrammed artificially through the introduction of endogenous transcription factors by using viruses like retrovirus to produce iPSCs (induced pluripotent stem cells). There are proteins that are important in the regulation of stem cell differentiation such as bone morphogenic protein -2 (BMP-2), leukocyte inhibitory factor and micro RNAs. Cutting edge research featuring stem cells will gear us to medical discovery of cell-based therapies of various diseases occurring in... view more»

DOI: 10.4172/2325-9620.1000126

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