Yun Ho Lee Author

Short Communication Open Access

A case of high grade Myxofibrosarcoma of the lower leg

Author(s):

Yun Ho Lee

Myxofibrosarcoma, also known as myxoid malignant fibrous histiocytoma, is one of the most common fibroblastic sarcomas in the older patient. It
occurs mainly in the limbs and there is a tendency for predominantly subcutaneous, multinodular, diffusely infiltrative growth, which may extend
to the overlyin dermis and present as a cutaneous lesion. A 90-year-old female presented with solitary, 5cm sized, firm, fixed mass on right lower
leg with the onset of 2 months ago. The histologic examination of the lesion showed malignant spindle cell tumor with myxoid stroma. Many of
the cells were spindle or ovoid shape and elongated curvilinear capillaries were observed. Overall tumor cellularity was high and marked nuclear
atypical, more than 20 mitoses per 10 hi... view more»

Abstract PDF