International Journal of Mental Health & PsychiatryISSN: 2471-4372

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Yves Bureau Author

yves.bureau@lawsonimaging.ca 519-646-6100

Subjects of specialization
cAMP; Phosphodiestease; Serotonin; Zembrin extract; Sceletium tortuosum; Alzheimer?s disease

Affiliation
Lawson Health Research Institute, London, Ontario, N6A 4V2, Canada

Biography

EDUCATION 2002 PDF, Medical Biophysics, Lawson Health Research Institute 2001 Ph. D., Experimental Psychology, Carleton University 1994 M. Sc., Biology, Laurentian University 1991 B. Sc., Neuroscience, Laurentian UniversityPROFESSIONAL & ACADEMIC EXPERIENCE 2003- Lecturer, Graduate statistics course, University of Western Ontario. 2002- Post-doctoral Fellow, Statistical Consultant, Lawson Health Research Institute. 2000-2002 Post-doctoral Fellow, Pharmacology, Merck Frosst Canada & Co. 1995-2000 Statistics Tutor and Sessional Lecturer, Department of Psychology, Carleton University. 1994-1999 Graduate Teaching Assistant, Department of Psychology, Carleton University.

 

Publications

Review Article Subscription

Exploring Zembrin Extract Derived from South African Plant, Sceletium tortuosum in Targeting cAMP-driven Phosphodiesterase (PDE) Signaling in Alzheimer’s Disease: Synthesis of Evidence

Author(s):

Simon Chiu, Hana Raheb, Kristen Terpstra, JoshVaughan, Michel Farina-Woodbury, Yves Bureau, Zack Cernovsky, Jirui Hou, John Copen, Mariwan Husni, Vladimir Badmeav, Ana Hategan, Mujeeb Shad, Zach Suntras, Nigel Gericke

Recently with the changing landscape of the aging population and the increase in incidence of Alzheimer’s disease (AD), there has been marked interest to develop strategies to prevent, delay and modify AD. We review the diverse lines of evidence in support of the emerging role of cAMP-mediated Phosphodiesterase (PDE) signalling with respect to aging, inflammation and depression. In view of the link of PDE to Epigenetic complex, targeting PDE through designing modulators and inhibitors of PDE may represent a novel approach in AD therapeutics. We... view more»

DOI: 10.4172/2471-4372.1000104

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