Advances in Genetic Engineering & BiotechnologyISSN: 2324-9021

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Editorial, Adv Genet Eng Biotechnol Vol: 2 Issue: 1

Creutzfeldt-Jakob Disease Susceptibility: An Approach to Discovering Multiple Candidate Genes for Human Prion Diseases

Byung-Hoon Jeong* and Yong-Sun Kim
Ilsong Institute of Life Science, Hallym University, Anyang, Gyeonggi-do 431- 060, Republic of Korea
Corresponding author : Dr. Byung-Hoon Jeong
Ilsong Institute of Life Science, Hallym University, Anyang, Gyeonggi-do 431-060, Republic of Korea
Tel: 82-31-380-1981; Fax: 82-31-388-3427
E-mail: [email protected]
Received: October 26, 2012 Accepted: October 29, 2012 Published: November 02, 2012
Citation: Jeong BH, Kim YS (2012) Creutzfeldt-Jakob Disease Susceptibility: An Approach to Discovering Multiple Candidate Genes for Human Prion Diseases. Adv Genet Eng Biotechnol 1:2. doi:10.4172/2324-9021.1000e105

Abstract

Creutzfeldt-Jakob Disease Susceptibility: An Approach to Discovering Multiple Candidate Genes for Human Prion Diseases

Human prion diseases, including Creutzfeldt-Jakob disease (CJD), the most common human prion disease, are fatal neurodegenerative disorders. They are characterized by the accumulation of an abnormal prion protein (PrPSc), vacuolation, astrocytic gliosis and neuronal cell loss in the brain

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