Editorial, Adv Genet Eng Biotechnol Vol: 2 Issue: 1
Creutzfeldt-Jakob Disease Susceptibility: An Approach to Discovering Multiple Candidate Genes for Human Prion Diseases
| Byung-Hoon Jeong* and Yong-Sun Kim | |
| Ilsong Institute of Life Science, Hallym University, Anyang, Gyeonggi-do 431- 060, Republic of Korea | |
| Corresponding author : Dr. Byung-Hoon Jeong Ilsong Institute of Life Science, Hallym University, Anyang, Gyeonggi-do 431-060, Republic of Korea Tel: 82-31-380-1981; Fax: 82-31-388-3427 E-mail: bhjeong@hallym.ac.kr |
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| Received: October 26, 2012 Accepted: October 29, 2012 Published: November 02, 2012 | |
| Citation: Jeong BH, Kim YS (2012) Creutzfeldt-Jakob Disease Susceptibility: An Approach to Discovering Multiple Candidate Genes for Human Prion Diseases. Adv Genet Eng Biotechnol 1:2. doi:10.4172/2324-9021.1000e105 |
Abstract
Creutzfeldt-Jakob Disease Susceptibility: An Approach to Discovering Multiple Candidate Genes for Human Prion Diseases
Human prion diseases, including Creutzfeldt-Jakob disease (CJD), the most common human prion disease, are fatal neurodegenerative disorders. They are characterized by the accumulation of an abnormal prion protein (PrPSc), vacuolation, astrocytic gliosis and neuronal cell loss in the brain