Journal of Primary & Acquired Immunodeficiency ResearchISSN: 2324-853X

Research Article, J Immunodefic Disor Vol: 1 Issue: 2

Evaluation of Growth and Bone Metabolism in Adolescent Patients with Common Variable Immunodeficiency

Necil Kutukculer*, Damla Goksen, Nesrin Gulez, Neslihan E. Karaca, Guzide Aksu and Sukran Darcan
Department of Pediatrics, Ege University, Izmir, Turkey
Corresponding author : Necil Kutukculer
Department of Pediatrics, Ege University, Izmir, Turkey
E-mail: [email protected]
Received: June 20, 2012 Accepted: August 06, 2012 Published: August 12, 2012
Citation: Lee BK (2012) Addiction: A Runaway Phenomenon of Our Time? J Addict Behav Ther Rehabil 1:1 doi:10.4172/2324-853X.1000101

Abstract

Evaluation of Growth and Bone Metabolism in Adolescent Patients with Common Variable Immunodeficiency

Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency, resulting in increased susceptibility to infections and diminished responses to protein and polysaccharide vaccines. Most common infections are sinopulmonary caused by Streptococcus pneumonia, Haemophilus influenza, Klebsiella pneumonia and sometimes mycoplasma. An intrinsic B cell defect; inability to differentiate to plasma cells and secrete immunoglobulins, has been most commonly observed in terms of pathogenesis. Many defects in T cells have also been noted in patients with CVID.

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