Immunology of hepatobiliary systems
The hepatobiliary system is essential for digestion and includes: the liver, pancreas, bile ducts and the gallbladder. Many disorders and diseases can affect these organs of hepatobiliary system. The liver contains numerous innate and adaptive immune cells that specialize in detection and capture of pathogens. Liver has unique immunoregulatory functions. Immunology deals with the defence mechanisms including all physical, chemical and biological properties of the organism that help it to combat its susceptibility to foreign organisms, material, etc. Many types of liver-resident antigen-presenting cells have immune regulatory function and they can also induce the differentiation of circulating immune cells into regulatory cells. This section deals with the understanding of chronic viral infection of the liver, autoimmune liver disease, and liver transplantation, transplantation immunology, hypersensitivities, immune deficiency, nonalcoholic fatty liver disease, and the immunogenetics of autoimmune liver disease. Immunological diseases of the hepatobiliary system and the pancreas include a broad spectrum of disorders that manifest characteristic histopathology/serology and variable clinical features and imaging findings. The Journal of Liver: Disease & Transplantation addresses both the liver pathology and liver transplantation. JLDT stands among the liver journals in the globe. The major areas of journal include advances in liver diseases, liver trauma, portal hypertension and pediatric liver tumors. Journal of Liver: Disease & Transplantation focuses on the topics hepatitis, cirrhosis, liver cancer, alcohol damage, fatty liver, metabolic and genetic liver diseases, autoimmune liver diseases, liver transplantation and techniques, surgical complications and transplantation outcomes. The Journal is using quality and standard peer review process with help of Editorial and review board members for its paper publications. It is also using online manuscript submission and manuscript tracking systems.