Andrology & Gynecology: Current ResearchISSN: 2327-4360

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Research Article, Androl Gynecol Curr Res Vol: 3 Issue: 3

Is N-acetylcysteine a better Insulin Sensitizer than Metformin in Polycystic Ovarian Syndrome?

Mandira Dasgupta*, Tapas Kumar Roy, Partha Sarathi Mitra, Sudhir Adhikari and Tarashankar Bag
Department of Obstetrics and Gynecology, Medical College Kolkata, Calcutta University, Kolkata, West Bengal, India
Corresponding author : Mandira Dasgupta
Associate Professor, Department of Obstetrics and Gynecology, Medical College, Kolkata 88, College Street, Kolkata-700 073, India
Tel: 9831106193; E-mail: [email protected]
Received: June 04, 2015 Accepted: September 20, 2015 Published: September 27, 2015
Citation: Dasgupta M, Roy TK, Mitra PS, Adhikari S, Bag T (2015) Is N-acetylcysteine a better Insulin Sensitizer than Metformin in Polycystic Ovarian Syndrome? Androl Gynecol: Curr Res 3:3. doi: 10.4172/2327-4360.1000139

Abstract

Is N-acetylcysteine a better Insulin Sensitizer than Metformin in Polycystic Ovarian Syndrome?

The primary objective of this study was to examine the effect of NAC on IR by HOMA-IR compared to that of MET in PCOS patients. The secondary objectives were to study their effects on other parameters: BMI, waist circumference, fasting blood glucose, fasting insulin, serum testosterone and clinical improvement of hyperandrogenic features.

Keywords: N-acetylcysteine; Metformin; Polycystic ovarian syndrome; Insulin resistance; HOMA-IR

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