Andrology & Gynecology: Current ResearchISSN: 2327-4360

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Research Article, Androl Gynecol Curr Res Vol: 2 Issue: 4

Metformin Exposure in Early Pregnancy and Spontaneous Abortions in Women with Polycystic Ovary Syndrome

Finn F. Lauszus*, Mette Viftrup-Lund and Melina Gade
Department of Gynecology and Obstetrics, Herning Hospital, Denmark
Corresponding author : Finn Lauszus, PhD, MD
Associate Professor, Research Specialist, Gynecology Department, Herning Hospital, Gl Landevej 61, DK- 7400 Herning, Denmark
Tel:+4578434614; Fax: +4578434636; E-mail: [email protected]
Received: May 20, 2014 Accepted: September 20, 2014 Published: September 25, 2014
Citation: Lauszus FF, Viftrup-Lund M, Gade M (2014) Metformin Exposure in Early Pregnancy and Spontaneous Abortions in Women with Polycystic Ovary Syndrome. Androl Gynecol: Curr Res 2:4. doi: 10.4172/2327-4360.1000128

Abstract

Metformin Exposure in Early Pregnancy and Spontaneous Abortions in Women with Polycystic Ovary Syndrome

We sought to determine whether metformin affects the rate of first trimester spontaneous abortions and congenital malformations in women with PCOS. Design. Consecutive series of metformin treated women with a questionnaire followup. Setting. Department of Gynecology and Obstetrics at Herning and Holstebro Hospital. Population. 117 women with PCOS treated with metformin prior to and during early pregnancy. 

Keywords: Metformin;Pregnancy;Spontaneous abortion; Malformation; Polycystic ovary syndrome

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