International Journal of Cardiovascular ResearchISSN: 2324-8602

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Editorial, Int J Cardiovasc Res Vol: 1 Issue: 3

Mitochondria, the Cardiomyocyte Power plant: Sugar-Fueled Power Outages and Toxic Waste

Waiho Tang, Kathleen Martin and John Hwa*
Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 George St Level 7, New Haven CT 06511,USA
Corresponding author : John Hwa
Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 George St Level 7, New Haven CT 06511, USA
E-mail: [email protected]
Received: September 26, 2012 Accepted: September 28, 2012 Published: October 01, 2012
Citation: Tang W, Martin K, Hwa J (2012) Mitochondria, the Cardiomyocyte “Power plant”: Sugar-Fueled Power Outages and Toxic Waste. Int J Cardiovasc Res 1:3 doi:10.4172/2324-8602.1000e109

Abstract

Mitochondria, the Cardiomyocyte “Power plant”: Sugar-Fueled Power Outages and Toxic Waste

Diabetes mellitus increases the risk for cardiovascular disease including coronary artery disease, hypertension, and heart failure.Studies have now convincingly demonstrated that ventricular dysfunction and heart failure in diabetic patients (diabetic cardiomyopathy) can be independent of coronary artery disease or hypertension. Intensive investigations are underway to decipher the underlying molecular mechanisms. Cardiac myocytes rely on high numbers of mitochondria, the cellular “power plant”, to produce the energy for contraction cycles.

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