Andrology & Gynecology: Current ResearchISSN: 2327-4360

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Review Article, Androl Gynecol Curr Res Vol: 1 Issue: 3

Molecular Pathology and Therapy of Endometriosis: Revisited

Padmanaban S Suresh1*, Thejaswini Venkatesh2, Thangarasu Rajan3 and Rie Tsutsumi4
1Centre for Biomedical Research, Vellore Institute of Technology (VIT), Tamilnadu, India
2Dept of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India
3Aarupadai Veedu Medical College and Hospital, Puducherry, India
4University of Tokushima, Institute of Health Bioscience, Department of Public health and nutrition, Japan
Corresponding author : Suresh PS, PhD
Centre for Biomedical Research, Vellore Institute of Technology, VIT University, Vellore - 632 014, Tamilnadu, India
Tel: 91-9597872269; E-mail: [email protected]
Received: April 05, 2013 Accepted: May 17, 2013 Published: May 22, 2013
Citation: Suresh PS, Venkatesh T, Rajan T, Tsutsumi R (2013) Molecular Pathology and Therapy of Endometriosis: Revisited. Androl Gynecol: Curr Res 1:3. doi:10.4172/2327-4360.1000105

Abstract

Molecular Pathology and Therapy of Endometriosis: Revisited

Endometriosis is among one of the most challenging diseases of the 21st century that affects women in their reproductive age, and its aetiology and pathogenesis remains enigmatic. Unravelling the molecular mechanisms that play a role in the etiopathogenesis of endometriosis has been the subject of intense investigation over the last decade. It is a complex hormone dependent and multifactorial disease involving intricate communications of genetic, immunological, hormonal and environmental factors and the clear understanding of the etiopathogenesis of endometriosis is scarce, as indicated by many studies and recent setbacks in clinical trials.

Keywords: Pathogenesis;Angiogenesis;Autoimmunity;Estradiol; Clinical trials; Endometriosis

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