International Journal of Cardiovascular ResearchISSN: 2324-8602

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Research Article, Int J Cardiovas Res Vol: 5 Issue: 3

Clinical and Laboratory characteristics of patients presenting to the Emergency Department with Hypertensive urgency

Shachaf Shiber-Ofer1,4*, Zipora Shohat2,4 and Alon Grossman3,4
1The Department of Emergency Medicine, Rabin Medical Center, Beilinson Campus, Israel
2Bio-statistical institute, Rabin Medical Center, Beilinson Campus, Israel
3Endocrinology and Metabolism Institute, Rabin Medical Center, Beilinson Campus, Israel
4Sackler Faculty of Medicine, Tel Aviv University, Israel
Corresponding author : Shachaf Shiber-Ofer
Emergency department, Beilinson Hospital, Rabin Medical Center Petach Tikva 49100, Israel
Tel: +972-03-937000
Fax: +972-03-9377062
E-mail: [email protected]
Received: March 21, 2016 Accepted: May 12, 2016 Published: May 19, 2016
Citation: Shiber-Ofer S, Shohat Z, Grossman A (2016) Clinical and Laboratory characteristics of patients presenting to the Emergency Department with Hypertensive urgency. Int J Cardiovasc Res 5:3. doi:10.4172/2324-8602.1000266

Abstract

Background: Clinical and laboratory characteristics of individuals presenting to the emergency department (ED) with hypertensive urgency (HU) are not well characterized. Methods: In a retrospective chart review study, 150 consecutive patients admitted to a tertiary care center ED with HU (systolic blood pressure values >180 mmHg or diastolic blood pressure values > 110 mmHg without evidence of end organ involvement) were compared with 150 patients with normal blood pressure evaluated in the surgical ward of the same emergency room. Demographic variables, co-morbidities and laboratory values were compared between the two groups. Results: HU patients were older (66 ± 16.1 years vs. 61.7 ± 19 years, p=0.04), had a greater prevalence of hypertension 90% vs. 64%, p=0.001), were treated with more anti-hypertensive medications (1.9 ± 1.4 vs. 1 ± 1.3, p=0.001) and had a higher prevalence of chronic kidney disease (10.6% vs. 4% p=0.044). Laboratory findings were similar in HU and normotensive individuals except for EGFR (82.40+27.76 mg/dl vs. 89.36+24.80 mg/dl, p=0.02) and CPK (124.93+93.73 mg/dl vs. 165.43+137.42 mg/dl, p=0.003). Conclusions: HU in an ED setting is more prevalent among elderly, hypertensive individuals, particularly among those with chronic kidney disease

Keywords: Hypertensive urgency; Emergency department; Troponin; Kidney disease

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