International Journal of Cardiovascular ResearchISSN: 2324-8602

Reach Us +1 850 900 2634
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article, Int J Cardiovasc Res Vol: 5 Issue: 1

Effect of Phase 2 Cardiac Rehabilitation Program on High Sensitivity C-Reactive Protein Levels in Post-Percutaneous Coronary Intervention Patients

Ahmed Mohamed El Missiri* and Mohamed Awad Taher
Cardiology Department, Faculty of Medicine, Ain Shams University, Abbassia, Cairo, Egypt
Corresponding author : Ahmed El Missiri
Cardiology Department, Ain Shams University, Faculty of Medicine, Abbassia, Cairo, Egypt
Tel: +20-10-016-14-717
E-mail: [email protected]
Received: December 11, 2015 Accepted: January 22, 2016 Published: January 29, 2016
Citation: El Missiri AM, Taher MA (2016) Effect of Phase 2 Cardiac Rehabilitation Program on High-Sensitivity C-Reactive Protein Levels in Post-Percutaneous Coronary Intervention Patients. Int J Cardiovasc Res 5:1. doi:10.4172/2324-8602.1000253

Abstract

Effect of Phase 2 Cardiac Rehabilitation Program on High Sensitivity C-Reactive Protein Levels in Post-Percutaneous Coronary Intervention Patients

Objective: To assess the effects of phase 2 cardiac rehabilitation program on hs-CRP levels in patients revascularized by percutaneous coronary intervention (PCI).

Methods: This study included 80 patients with a history of acute myocardial infarction or acute coronary syndrome for which total coronary revascularization had been performed by PCI. Patients were randomized into 2 equal groups; one enrolled in a cardiac rehabilitation program while the other was not. Risk factors and body mass index were assessed. Hs-CRP was measured at baseline then at the end of cardiac rehabilitation program or after three months for controls.

Results: There was no significant difference between study and control patients regarding baseline characteristics. At baseline, median hs-CRP was higher in the study group 2.36 (0.63-10.6) vs 1.68 (0.57-10.1) mg/L (p=0.012). For the study group, BMI dropped from 29.6 ± 4.5 to 28.9 ± 4.3 kg/m2 (p=0.002) and the number of active smokers was reduced (p<0.0001). Hs-CRP was reduced from 2.36 (0.63-10.6) to 1.63 (0.57-7.91) mg/L (p=0.0006). Significant reductions in hs-CRP levels were found in non-smokers (p=0.018), non-hypertensive (p<0.0001) and non-diabetic patients (p<0.0001). For the control group, there was no change in BMI at 3 months (p=0.422) nor hs-CRP (p=0.145). Comparing study and control groups at follow up, revealed a lower hs-CRP in the study group 1.63 (0.57-7.19) vs 2.4 (0.8-7.85) mg/L (p=0.003).

Conclusion: Participation in phase 2 cardiac rehabilitation program leads to a significant reduction in hs-CRP levels in patients with ischemic heart disease totally revascularized by PCI. Number of active smokers and BMI are also reduced.

Keywords: Cardiac rehabilitation program; Percutaneous coronary intervention; Acute myocardial infarction; Acute coronary syndrome

Track Your Manuscript

Share This Page

Media Partners