Reach Us +1 850 900 2634

International Journal of Cardiovascular ResearchISSN: 2324-8602

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article, Int J Cardiovasc Res Vol: 8 Issue: 3

Electrocardiogram Changes in Cancer Patients Taking 5-Flurouracil Chemotherapy at National Cancer Institute - University of Gezira (2018)

Abderrahman Ahmed Mohamed Ismail, Mawia Mohamed Ali Alhassan and Abdelmuniem Siddig Mohamed Ahmed*

University of Gezira, Sudan

*Corresponding Author: Abdelmuniem Siddig Mohamed Ahmed
University of Gezira, Khartoum, Sudan
Tel: +249912869216
E-mail: [email protected]

Received: May 03, 2019 Accepted: June 28, 2019 Published: July 05, 2019

Citation: Ismail AAM, Alhassan MMA, Ahmed ASM (2019) Electrocardiogram Changes in Cancer Patients Taking 5-Flurouracil Chemotherapy at National Cancer Institute - University of Gezira (2018). Int J Cardiovasc Res 8:3. doi: 10.4172/2324-8602.1000380

Abstract

Objective: To assess electrocardiogram changes in cancer patients taking 5-flurouracil chemotherapy at national Cancer institute- University of Gezira 2018.

Methods: This is a prospective, cross-section and analytical study, conducted to assess Electrocardiogram changes in cancer patients taking 5-flurouracil chemotherapy at national Cancer institute- university of Gezira in period between Septembers to December 2018. 100 patients diagnosed with cancer and on 5FU chemotherapy were included in the study.

Results: ECG records changed post 5 FU in 29% of patients. 4% have left axis deviation. 5% have right bundle branch block, 3% have inverted T wave, 5% have corrected QT interval between 0. 471-0.50 second and 3% more than 0.50 second, 2% developed left ventricular hypertrophy, 7% have a low voltage compared with ECG records before taking 5FU. No change in rhythm or ST segment. No relation between mode of administration and ECG changes. There was a relation between number of cycles and the heart rate after the treatment and between number of cycles and T wave inversion after the treatment.

Conclusions: 5-flurouracil chemotherapy cause electrocardiogram changes as an indicator of cardio toxicity effect of the drug.

Keywords: 5-flurouracil; Electrocardiogram; Cardio toxicity; Chemotherapy

Track Your Manuscript

Share This Page

Media Partners