International Journal of Cardiovascular ResearchISSN: 2324-8602

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Research Article, Int J Cardiovasc Res Vol: 6 Issue: 6

Impact of Balloon Mitral Valvuloplasty on Net Atrioventricular Compliance and Echocardiographic Assessment of Mitral Valve Area by Pressure Half Time versus Proximal Isovelocity Surface Area

Karthik Seetharam1, Mohamed Ahmed Abdel-Rahman2, Hala Raslan3, Osama Rifaie2 and Alaa Mabrouk Salem Omar1,3*

1Ichan School of Medicine at Mount Sinai, New York, NY, USA

2Department of Cardiology, Ain Shams University, Abbasiya, Cairo, Egypt

3Department of Internal Medicine, Medical Division, National Research Centre, Dokki, Cairo, Egypt

*Corresponding Author : Alaa Mabrouk Salem Omar, MD, Ph.D
Medical Division, Department of Internal Medicine, National Research Centre, Dokki, El-Buhouth St. Dokki, Cairo, 12311, Egypt
Tel: +2-02-33371362
Fax: +2-02-33370931

Received: July 14, 2017 Accepted: October 21, 2017 Published: October 26, 2017

Citation: Seetharam K, Abdel-Rahman MA, Raslan H, Rifaie O, Omar AMS (2017) Impact of Balloon Mitral Valvuloplasty on Net Atrio-ventricular Compliance and Echocardiographic Assessment of Mitral Valve Area by Pressure Half Time versus Proximal Iso-velocity Surface Area. Int J Cardiovasc Res 6:6. doi: 10.4172/2324-8602.1000333



 Background: We studied the relations between net-atrioventricular compliance (Cn) and balloon mitral valvuloplasty (BMV) and tested effects of Cn on mitral valve area by proximal isovelocity surface area (MVAPISA) and pressure half time (MVAPHT) before and after BMV.

Methods and Results:

Thirty-six BMV candidates were studied. Echocardiography was done before, immediately after BMV for all patients and 1-month after BMV for 13 patients. MVA was calculated invasively, (MVAGorlin, reference method), by planimetry (MVAPLN), in addition to PHT and PISA. Differences from MVA-PLN were calculated as d-PHT and d-PISA and Cn was calculated (1270 X (MVA-PLN/E-slope). Mean age was 36.1 ± 12.5 years, 25(69%) were females, 8(22%) were in atrial fibrillation. MVAPHT correlated with MVAGorlin after, but not before, BMV (r= 0.53, 0.240, p= 0.014, 0.202). MVAPISA correlated with MVAGorlin after and before BMV(r= 0.85, 0.89, all p<0.001). Both MVAPHT, and MVAPISA correlated with MVAPLN 1-month after BMV (r=0.58, 0.92, p<0.001, =0.048). d-PHT showed similar pattern of negative correlations with Cn before, immediately after, and 1 month after BMV (r= 0.69, 0.76, 0.69, p= <0.001,<0.001, =.013), while d-PISA did not. Cn independently predicted persistent pulmonary hypertension after BMV.

Conclusion: MVAPHT, unlike MVAPISA is extremely affected by Cn irrespective of the time of measurement in relation to BMV. Cn is a major determinant of persistent pulmonary hypertension after BMV.

Keywords: Mitral stenosis; Balloon mitral valvuloplasty; Net atrioventricular compliance; Proximal iso-velocity surface area; Pressure half time.

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