International Journal of Cardiovascular ResearchISSN: 2324-8602

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Research Article, Int J Cardiovasc Res Vol: 5 Issue: 1

Is C-reactive Protein Related to Cardiovascular Risk Factors in Brazilian Patients undergoing Coronary Angiography?

Sandra Maria Barbalho1*, Ricardo José Tofano2, Marcelo Dib Bechara1, Karina Quesada1, Claudemir Gregório Mendes1,Daniel Pereira Coqueiro3, Ariádine Augusta Maiante4, Beverli Alexandrina de Oliveira4 and Dayane Screpante Marques4
1Professor at the Department of Biochemistry and Cellular Biology – Medical School of Marília – UNIMAR, Av. Higino Muzzi Filho 1001, Marília, SP, Brazil
2Cardiologist of the Cardiac Surgery Unit and Hemodynamics - Medical School,Marília, SP, Brazil
3Professor of “Faculdade de Ensino Superior do Interior Paulista” - FAIP -Marília, SP, Brazil
4Medical Doctor - Medical School - Marília, SP, Brazil
Corresponding author : Sandra Maria Barbalho
Department of Biochemistry and Cel lular Biology – Medical School of Marília – UNIMAR, Av. Higino Muzzi Filho 1001, Marília, SP, Brazil
Tel: 005514 33069434
E-mail: smbarbalho@gmail.com
Received: September 28, 2015 Accepted: December 28, 2015 Published: January 07, 2016
Citation: Barbalho SM, Tofano RJ, Bechara MD, Quesada K, Mendes CG, et al. (2016) Is C-reactive Protein Related to Cardiovascular Risk Factors in Brazilian Patients undergoing Coronary Angiography?. Int J Cardiovasc Res 5:1. doi:10.4172/2324-8602.1000251

Abstract

Is C-reactive Protein Related to Cardiovascular Risk Factors in Brazilian Patients undergoing Coronary Angiography?

Objective: To determine plasma levels of high sensibility C - reactive protein (hs-CRP) in patients undergoing coronary angiography and compare them with the components of the Metabolic Syndrome.

Methods: Socio-economic, anthropometric and biochemical data from 95 patients undergoing coronary arteriography were collected.

Results: The profiles of three groups of hs-CRP (low, moderate and high) were statistically equal in gender (p=0.625), age (p=0.879), smoking (p=0.800), alcohol consumption (p=0.560), practice physical activity (p=0.636), presence of diabetes (p=0.530), hypertension (p=0.207), SM (p=0.121), use of statins (p=0.472), total cholesterol (p=0.329) HDL-c levels (p=0.288), LDL-c (p=0.940), triglycerides (p=0.386), glucose (p=0.232), waist circumference (p=0.377), the presence of plaques (p=0.181) and catheterization of the report (p=0.207). Besides, there are more obese patients at high hs-CRP class (p=0.012).

Conclusion: Although the CRP is associated with cardiovascular morbidity and it is strongly linked to the components of Metabolic Syndrome, in the patients undergoing coronary angiography evaluated in this study, a significant difference was observed only for the presence of obesity.

Keywords: C-reactive Protein; Metabolic syndrome; Angiography; Atherosclerosis

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