Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi Editorial, Vol: 8 Issue: 5
Sarcopenia: A Growing Challenge in Aging Populations
Dr. Daniel Bavisetti*
Department of Geriatric Medicine, India
- *Corresponding Author:
- Dr. Daniel Bavisetti
Department of Geriatric Medicine, India
E-mail: daniel.bavisetta@example.com
Received: 01-Sep-2025, Manuscript No. agm-25-176143; Editor assigned: 3-Sep-2025, Pre-QC No. agm-25-176143 (PQ); Reviewed: 17-Sep-2025, QC No. agm-25-176143; Revised: 24-Sep-2025, Manuscript No. agm-25-176143 (R); Published: 30-Sep-2025, DOI: 10.4172/2576-3946.1000197
Citation: Daniel B (2025) Sarcopenia: A Growing Challenge in Aging Populations. J Aging Geriatr Med 8: 197
Introduction
Sarcopenia, Muscle Loss, Aging, Frailty, Muscle Strength, Functional Decline, Geriatric Medicine, Nutrition, Resistance Training, Older Adults
Introduction
Sarcopenia is characterized by a gradual decline in skeletal muscle mass, strength, and physical performance as individuals age. Recognized as a key component of frailty, sarcopenia increases the risk of falls, fractures, hospitalization, and mortality among older adults. While muscle loss is a natural consequence of aging, the condition becomes clinically significant when it interferes with daily functioning and independence [1,2].
Multiple mechanisms contribute to the development of sarcopenia. These include hormonal changes, chronic inflammation, neuromuscular degradation, mitochondrial dysfunction, decreased physical activity, and inadequate nutrition. Additionally, chronic illnesses such as diabetes, cardiovascular disease, cancer, and renal impairment further accelerate muscle degeneration.
Diagnostic guidelines from groups like the European Working Group on Sarcopenia in Older People (EWGSOP) emphasize the assessment of muscle strength, muscle quantity, and physical performance. Tools such as handgrip strength measurement, DXA or bioimpedance analysis, and gait speed testing are commonly used in clinical and research settings [3,4].
The global rise in life expectancy increases the urgency for effective strategies to mitigate sarcopenia. Early identification and targeted interventions can help preserve functional capacity, reduce the healthcare burden, and improve quality of life for aging individuals [5].
Conclusion
Sarcopenia represents a major public health concern affecting older adults worldwide. Its impact on functional ability, independence, and overall well-being highlights the need for greater clinical attention and preventive strategies. Evidence supports the use of resistance training, adequate dietary protein, and vitamin D supplementation as foundational approaches to management. Integrating sarcopenia screening into routine geriatric assessments and promoting active lifestyles can substantially reduce disease progression. Continued research and awareness are essential for improving outcomes and enhancing the quality of life among aging populations.
References
- Danafar H (2016) High performance liquid chromatographic method for determination of Ezetimibe in pharmaceutical formulation tablets. Pharm Biomed Res 2: 38-46.
- Praveen Kumar (2012) A stability indicating RP-HPLC method development for determination of Ezetimibe in tablet dosage form. Der Pharma Chemica 4: 1296-1304.
- Raul (2015) RP-HPLC Method Development and Validation for the Simultaneous Estimation of Atorvastatin and Ezetimibe in Pharmaceutical Dosage Form. Asian J Pharm Clin Res 8: 178-181.
- El-Bagary (2014) LC-MS-MS Simultaneous Determination of Atorvastatin and Ezetimibe in Human Plasma. J Chromatogr Sci 52: 773-780.
- Suneela D, Dhaneshwar S, Deshpande P, Patil M (2007) Development and validation of a method for simultaneous densitometric estimation of Atorvastatin calcium and Ezetimibe as the bulk drug and in tablet dosage forms. Acta Chromatogr 19: 141-148.
- Danafar H (2016) High performance liquid chromatographic method for determination of Ezetimibe in pharmaceutical formulation tablets. Pharm Biomed Res 2: 38-46.
