Journal of Pharmaceutics & Drug Delivery ResearchISSN: 2325-9604

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A New coumarin-secoiridoid from the stem bark of the Algerian medicinal plant Fraxinus xanthoxyloides


Dr. Aldjia Hadrou

Department of Chemistry, Med Boudiaf University, Algeria

: J Pharm Drug Deliv Res

Abstract


This paper deals with the isolation and structure identification of the new compound isofraxisecoside, a coumarinsecoiridoid diglucosides along with nine known compounds. To the best of our knowledge, isofraxisecoside, is the third example of a natural compound consisting of one coumarin glucoside unit linked to a secoiridoid moiety of oleoside type and no phytochemical investigation has been carried out on the Algerian species Fraxinus xanthoxyloides (G.Don) Wall. ex A.DC. The molecular structures of the isolated compounds were mainly elucidated by the use of NMR techniques 1D and 2D (1H, 13C, DEPT, HSQC, HMBC and ROESY), high resolution mass spectrometry (HR-ESI-MS), measurement of the optical rotation [α]D20 and by comparison with the literature data.

Biography


Department of Chemistry, Med Boudiaf University, Algeria

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