Antimicrobial use in aquaculture: Patterns and current knowledge on its contribution to the emergence and spread of antimicrobial resistance
Lucia Santos
University of Coimbra, Portugal
: Med Microbiol Rep
Abstract
Aquaculture is a fast-growing industry accounting nowadays for almost half of the fish supplies for human consumption, worldwide. The intensive and semiintensive practices used to produce large stocks of fish, in small spaces, originate frequent disease outbreaks and, to control it, the use of antimicrobials, for prophylactic and therapeutic purposes, is a customary practice. The selective pressure exerted by these drugs – usually present in sub-therapeutic doses for prolonged periods, in water and sediments – represent the ideal framework for the emergence and selection of resistant bacterial strains, promoting and stimulating horizontal gene transfer. Passage of antimicrobial resistant genes and antimicrobial-resistant bacteria from aquatic to terrestrial animal husbandry and to human environments, and vice versa, with detrimental effects on both human and animal health, and also in aquatic ecosystem, is now largely recognized. A global effort must be developed in order to cease antimicrobial overuse in aquaculture, encouraging stakeholders to adopt other disease preventive measures, such as adequate hygiene standards, vaccines or probiotics, among others. Shaping a new path is crucial, in order to contain the increasing threat of antimicrobial resistance. Being antimicrobial resistance a global ecological event, the One Health strategy is the most appropriate way to address and tackle it. As postulated by One Health principle we must recognize that human, animal and environmental health are interconnected, that diseases are transmitted from humans to animals, and vice versa, and must therefore be tackled in both.
Biography
Lúcia Santos is a pharmacist, Master in Public Health, presently perusing her PhD degree in Food Security in Coimbra University – Portugal. Her investigation work has been focusing on food security, essentially related to the presence of antimicrobial residues in fish and related consequences on public health. Special focus is being given on the impact of antibiotic use in aquaculture on the global health crisis of antimicrobial resistance.
E-mail: luciamlsantos@gmail.com
