Controlling drug resistant bacteria using graphene/ceramics nanocomposites
Aqsa Arshad
International Islamic University, Pakistan
: J Pharm Drug Deliv Res
Abstract
Antibiotic resistant bacteria are a serious threat to health not only in developing countries but also in developed countries. This is since bacteria gain resistance against traditional drugs over the time. A solution to completely eradicate different bacteria is presented in this work. Some novel nanocomposites that are comprised of graphene/X where X shows different ceramics i.e., MgO, SiO2, Fe3O4 and NiO are tested for their performance against different bacterial strains. A comparative study of these nanocomposites is presented in this work to inhibit the growth of Gram negative and Grampositive bacteria. By variation of amount of graphene in different nanocomposites is presented. It has been found that the growth of all the three bacterial strains under consideration, i.e., E. coli, S. aureus, and P. aeruginosa was completely inhibited by graphene/ NiO nanocomposites. Graphene/Fe3O4 also showed good antibacterial activity. However, graphene/ MgO and graphene/SiO2 showed only a moderate activity. In the light of findings, graphene/ NiO nanocomposites can be considered as an innovative material that provides an alternative for the eradicating drug resistant bacteria.
Biography
