Diclofenac sodium: Treatment of Rheumatic diseases

Nesar Ahmad

Diclofenac sodium: Treatment of Rheumatic diseases

Nesar Ahmad

Integral University, India

: J Pharm Drug Deliv Res

Abstract

Diclofenac is a medicine that works by reducing substances in the body that causes pain and inflammation. Diclofenac is used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis. The Cataflam brand of this medicine is also used to treat menstrual cramps. Diclofenac 75 to 150 mg daily (25 to 50 mg 3 times daily) is comparable in efficacy with ordinary aspirin 3 to 5g daily and indomethacin 75 to 150 mg daily in rheumatoid arthritis and with indomethacin in osteoarthritis Diclofenac powder (Cambia) is used to treat a migraine headache attack. It will not prevent headaches or reduce the number of attacks if Diclofenac is not used in the combination. If patient have a history of allergic reaction to aspirin or NSAIDs it can increase the risk of fatal heart attack or stroke, especially if he use it long term or take high doses, if he suffering from heart disease. Although there is some evidence of Diclofenac efficacy when administered twice daily, or once daily as a slow release tablet. The drug is also available as suppositories and ampoules for intramuscular injection. It is not recommended just before or after heart bypass surgery (coronary artery bypass graft or CABG). These conditions can occur without warning while you are using this medicine, especially in older adults. Diclofenac should be considered along with other drugs of its type in the arthritic patient.