Erythromycin: An article of action of (Macrolide) lower and upper respiratory tract infection

Nesar Ahmad

Erythromycin: An article of action of (Macrolide) lower and upper respiratory tract infection

Nesar Ahmad

Integral University, India

: J Pharm Drug Deliv Res

Abstract

Erythromycin is an antibiotic in the class of antibiotics known as macrolide antibiotics which also includes azithromycin (Zithromax, Zmax) and clarithromycin (Biaxin). Erythromycin is similar in use to penicillin and is widely used for patients who are allergic to penicillin. Erythromycin stops bacterial growth and relies on the body's immune system to kill bacteria. It is used to treat several types of infections including upper/lower respiratory tract infections, skin infections, acute pelvic inflammatory disease, erythrasma, etc caused by bacteria such as Streptococcus pyogenes, Streptococcus pneumoniae, Mycoplasma pneumoniae, Staphylococcus aureus, Neisseria gonorrhoeae, and many others. Erythromycin, like all macrolide antibiotics, prevents bacterial cells from growing and multiplying by interfering with their ability to make proteins while not affecting human cells. Bacteria such as Haemophilus influenzae are resistant to erythromycin alone and must be treated with a combination of erythromycin and adequate doses of sulfonamides. The FDA approved E.E.S in April 1965. Tablets: 250, 333, 400 and 500 mg. Suspension: 200 and, 400 mg/teaspoon. Tablet (Chewable): 200 mg. Powder: 100 mg/half-teaspoon and 200 mg/teaspoon. Granules: 200 and 400 mg/teaspoon. Powder for Injection: 500 mg and 1g side effect are severe stomach pain, nausea, vomiting, or diarrhea fever, skin rash, redness, or itching, unusual tiredness or weakness. Erythromycin also is used in patients who are allergic to penicillin for the prevention of recurrent rheumatic fever and infections of the hearts' valves (endocarditis)) in patients with valvular abnormalities of the heart before they undergo dental treatments.