Shaping a pharma manufacturing facility design through a ready-to-fill primary packaging solution

Gabriele Peron

Shaping a pharma manufacturing facility design through a ready-to-fill primary packaging solution

Gabriele Peron

Stevanato Group, Italy

: J Pharm Drug Deliv Res

Abstract

Industry trends towards lesser time taken to market and smaller batch sizes make new investment in large sterile manufacturing facilities difficult to justify. Production spaces need design that incorporate the flexibility required for the new business models. Concurrently, facility aging combined with increasingly challenging GMP requirements is driving the need for new technologies. These technologies include single-use product contact components, pre-sterilized container/closures and increased use of robotics in the processing. The integration of engineering design, business needs and supplier technologies will help the next generation of sterile manufacturing facilities. At the same time, there is a clear need to increase sterility assurance levels, increase productivity and get a faster access to market, with reduced investments as urgent priorities. This paper illustrates the direct impact on pharma manufacturing facility design due to the adoption of technologies based on the concept of ready-to-use platform.