Journal of Primary & Acquired Immunodeficiency ResearchISSN: 2324-853X

Editorial, J Immunodefic Disor Vol: 1 Issue: 1

Reciprocal Interaction between Commensal Microbiota and Mucosal Immune System

Qiurong Li*
Research Institute of General Surgery, Jinling Hospital, Nanjing University, Nanjing, China
Corresponding Author : Qiurong Li
Research Institute of General Surgery, Jinling Hospital, Nanjing 210002, China
E-mail: [email protected]
Received: June 21, 2012 Accepted: June 21, 2012 Published: June 23, 2012  doi:10.4172/2324-853X.1000e103
Citation: Koichi S. Kobayashi (2012)NLRC5/CITA: A Novel Regulator of Class I Major Histocompatibility Complex Genes. J Immunodefic Disor 1:1. doi:10.4172/2324-853X.1000e103

Abstract

Reciprocal Interaction between Commensal Microbiota and Mucosal Immune System

The human gut harbors an approximate 100 trillion microorganisms including bacteria, fungi, protozoans and viruses. These organisms constitute an exceptionally diverse and dynamic microbial ecosystem. The vast majority of gut microbiota is bacteria, which comprised of 500-1000 different species. The enteric bacterial communities play crucial roles in the maintenance of intestinal homoeostasis and the protection against colonization by opportunistic pathogens.Intestinal mucosal surfaces directly interface with a dense and diverse microbial population. Under normal circumstances, the host could peacefully exist together with these vast, diverse and dynamic bacterial populations and their potentially inflammatory components.

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