About Clinical Pharmacokinetic

Pharmacokinetic is the study of drug absorption, distribution with in body, and drug elimination over time. Clinical Pharmacokinetic is the application of clinical pharmacokinetic principles to safe and effective therapeutic management of drugs in an individual patient. Enhancing efficacy and decreasing toxicity of patient’s drug therapy. When dose are increased for most drugs steady state concentration increased in a proportional fashion leading to linear pharmacokinetics. When steady state concentration in a disproportional fashion after the dose is altered drugs follow nonlinear pharmacokinetics.