ACP1 Genetic Polymorphism and Cardiac Hypertrophy

<p>Gloria-Bottini F, Banci M, Saccucci P, Neri A, Magrini A and Bottini E</p>

International Journal of Cardiovascular ResearchISSN: 2324-8602

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ACP1 Genetic Polymorphism and Cardiac Hypertrophy

ACP1 Genetic Polymorphism and Cardiac Hypertrophy

Platelet derived growth factors (PDGFs) exert an important role in contractile function of cardiomyocytes and protection from apoptotic cell death. Since ACP1is able to dephosphorylate PDGF receptors modulating their actions we have investigated the relationship between ACP1 genetic variability and cardiac hypertrophy.