Research Article, J Otol Rhinol Vol: 3 Issue: 4
Comparison of Neuropeptide Innervation in Allergic and Nonallergic Rhinitis
Ulas Eraydin1, Ceren Gunel2*, Leyla Didem Kozaci3, Muhan Erkus4 and H Sema Basak5 | |
1Ardahan Kahta State Hospital, Aydin, Turkey | |
2Department of Otolaryngology-Head and Neck Surgery, Adnan Menderes University Medical School Hospital, Aydin, Turkey | |
3Department of Medical Biochemistry, Adnan Menderes University Medical School Hospital, Aydin, Turkey | |
4Department of Medical Pathology, Adnan Menderes University Medical School Hospital, Aydin, Turkey | |
5Department of Otolaryngology-Head and Neck Surgery, Adnan Menderes University Medical School Hospital, Aydin, Turkey | |
Corresponding author : Ceren Gunel Adnan Menderes Universitesi Tip Fakultesi Hastanesi KBB AD, Aytepe Mevkii, 09100, Aydin, Turkey Tel: +90-533-7175693; Fax: + 90-256-2182037 E-mail: drgunel@hotmail.com |
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Received: April 10, 2014, Accepted: July 18, 2014 Published: July 23, 2014 | |
Citation: Ulas Eraydin, Ceren Gunel, Leyla Didem Kozaci, Muhan Erkus, H Sema Basak (2014) Comparison of Neuropeptide Innervation in Allergic and Nonallergic Rhinitis. J Otol Rhinol 3:4. doi:10.4172/2324-8785.1000166 |
Abstract
Comparison of Neuropeptide Innervation in Allergic and Nonallergic Rhinitis
Background: Rhinitis can be induced by different mechanisms and involves several etiological agents. It is important to differentiate between allergic rhinitis (AR) and nonallergic rhinitis (NAR), as management differs for each.
Objective: We aimed to study the several biomarkers of allergic rhinitis and nonallergic rhinitis to investigate their potential as outcome measures in clinical intervention trials.
Materials and Methods: All study groups were compared in terms of mucociliary clearance time, air flow level, and various neuropeptids in nasal fluid. All groups were evaluated for asthma by a respiratory medicine specialist performing pulmonary function testing.