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Hirofumi Kai

Hirofumi Kai

Hirofumi Kai, PhD
Advanced Biomedical Sciences
Kumamoto University, Japan

 

Biography

 Hirofumi Kai is currently working as researcher at Advanced Biomedical Sciences, Kumamoto University, Japan. Dr. Hirofumi Kai’s research areas are Molecular Medicine & Therapeutics.

Research Interest

Dr. Hirofumi Kai currently investigating the molecular mechanisms of diseases such as cystic fibrosis, amyloidosis and cancer. Our main goal is to elucidate the factors involved in these diseases which could ultimately provide useful information to develop therapy. Specifically, we study 1) the intracellular trafficking and degradation of CFTR, ABC transporters, and transthyretin, 2) the innate immunity molecules in the epithelial cells, 3) new ways of inducing preconditioning molecules for disease prevention, 4) cell biology of physical stress and development of physical medicine.

Publications

Editors & Editorial Board Members
none:  Mol Med Ther 2012, 1:1
doi: #
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Abstract  |   Full-text  |   PDF  |  
Editors & Editorial Board Members
none:  Mol Med Ther 2012, 1:2
doi:
Abstract  |   Full-text  |   PDF  |  
Human Fungal Infections: Need to Improve Diagnosis with New Biomarkers Developed by Translational Research
Editorial:  Mol Med Ther 2012, 1:1
doi: 10.4172/2324-8769.1000e101
Aamir Shahzad, Randall J Cohrs, Adong Shen and Cornelia Lass-Flörl
Abstract  |   Full-text  |   PDF  |  
Performance of Commercial Interferon-γ Release Assays for Screening Latent Tuberculosis Infection: A Meta-Analysis
Research Article:  Mol Med Ther 2012, 1:2
doi: 10.4172/2324-8769.1000103
Lin Sun, Qingqin Yin, Jianling Tian, Qing Miao, Fang Xu, Jing Xiao, Chen Shen, Weiwei Jiao, Cornelia Lass-Flörl, Aamir Shahzad and Adong Shen
Abstract  |   Full-text  |   PDF  |  
Parkinson’s Disease and Type-2 Diabetes: Methylglyoxal may be a Common Causal Agent; Carnosine could be Protective
Review Article:  Mol Med Ther 2012, 1:2
doi: 10.4172/2324-8769.1000104
Alan R. Hipkiss
Abstract  |   Full-text  |   PDF  |  
Prolyl Hydroxylases in fight or flight
Editorial:  Mol Med Ther 2012, 1:1
doi: 10.4172/2324-8769.1000e102
Anne-Theres Henze, Rodrigo Leite de Oliveira and Massimiliano Mazzone
Abstract  |   Full-text  |   PDF  |  
Genome-Scale Mapping of MicroRNA Signatures in Human Embryonic Stem Cell Neurogenesis
Research Article:  Mol Med Ther 2012, 1:2
doi: 10.4172/2324-8769.1000105
Xuejun H. Parsons, James F. Parsons and Dennis A. Moore
Abstract  |   Full-text  |   PDF  |  
Regulation of Coronary Vasomotor Function by Reactive Oxygen Species
Review Article:  Mol Med Ther 2012, 1:1
doi: 10.4172/2324-8769.1000101
Lih Kuo, Naris Thengchaisri and Travis W. Hein
Abstract  |   Full-text  |   PDF  |  
Novel Combinatorial Therapeutic Targeting of PAI-1(SERPINE1) Gene Expression in Alzheimer’s Disease
Short Communication:  Mol Med Ther 2012, 1:2
doi: 10.4172/2324-8769.1000106
Stacie M. Kutz, Craig E. Higgins and Paul J. Higgins
Abstract  |   Full-text  |   PDF  |  
Low Molecular Weight Antagonists of Plasminogen Activator Inhibitor-1: Therapeutic Potential in Cardiovascular Disease
Short Communication:  Mol Med Ther 2012, 1:1
doi: 10.4172/2324-8769.1000102
Tessa M. Simone and Paul J. Higgins
Abstract  |   Full-text  |   PDF  |  
 
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