International Publisher of Science, Technology and Medicine

Virology & Antiviral Research

Editorial Board

Jay C Brown

Editor-in-Chief:

Jay C. Brown, PhD
University of Virginia Cancer Center, USA

Read Interview session with Jay C. Brown

Biography :

Dr. Jay C Brown, Professor of Microbiology, Immunology, and Cancer Biology at University of Virginia Cancer Center, USA obtained his BA, Johns Hopkins University, Baltimore, MD. He was awarded the Ph.D. at Harvard University, Cambridge, MA, USA. Dr. Brown was a post-doctoral fellow at MRC Lab of Molecular Biology, Cambridge UK

 Biography
Research Interest :

Dr. Jay C Brown major research interests focus on Structure and Assembly of the Herpes Simplex Virus Capsid.

The Brown lab studies herpesvirus infections that affect cancer patients with emphasis on HSV-1 and KSHV. In both cases, the goal is to examine the structure and assembly of the virus capsid with the idea that such studies will suggest the nature of novel anti-herpes therapeutic agents directed against capsid assembly. Although most of the studies are carried out with HSV-1 and KSHV, it is expected that the results will clarify capsid assembly as it occurs in other herpes viruses and perhaps in other virus families as well.

Studies in the laboratory have defined the basic steps involved in capsid formation. Using an in vitro assembly system, they have recently clarified the way the portal becomes incorporated into capsids as they are assembled. The assembly project has led to the identification of an inhibitor of HSV-1 replication, WAY-150138, that acts by antagonizing incorporation of the portal as the capsid is formed. The lab is now attempting to define the mechanism of WAY-150138 action more closely and determine whether it or related thiourea compounds may be useful for therapy against herpesvirus infections.

 Research Interest
 Acceptance Letter
Nejat Duzgunes

Nejat Düzgüneş, PhD
Department of Biomedical Sciences
University of the Pacific, USA

Biography :

Nejat Duzgunes received his PhD from SUNY Buffalo. He was a National Cancer Institute Postdoctoral Fellow at UCSF, where he became an adjunct research faculty. He became Chair of the Department of Microbiology (1990) and Professor at the University of the Pacific School of Dentistry in San Francisco (1995). His current research interests are the gene therapy of oral cancer and mechanisms and inhibitors of HIV.

 Biography
Research Interest :
 Research Interest
Abdul A Waheed

Abdul A Waheed, PhD
Virus-Cell Intferaction Section
National Cancer Institute , USA

Biography :

Dr. Abdul Waheed is a Staff Scientist in Dr. Eric Freed's lab in the Virus-Cell Interaction Section, HIV Drug Resistance Program, NCI-Frederick. He received his Ph.D. in Membrane Biochemistry from the University of the Ryukyus, Okinawa, Japan in 1999. During his postdoctoral fellow at Tokyo Metropolitan Institute of Gerontology, Tokyo, Dr. Waheed showed the specific binding of theta-toxin (perfringolysin O) to cholesterol in the lipid rafts. He joined the National Institute of Diabetes and Digestive and Kidney Diseases in 2001, where he worked on the role of lipid rafts in G-protein signaling. Since 2003 he is working on host-factors involved in HIV-1 replication and small molecule inhibitors of HIV-1 replication

 Biography
Research Interest :

HIV-1 replication

 Research Interest
 Acceptance Letter
Li Wu

Li Wu, PhD
Department of Global Health
Ohio State University, USA

Biography :

Dr. Li Wu is a molecular virologist studying HIV interactions with host factors. His long-term research goal is to define the mechanisms regulating HIV infection in myeloid-lineage cells and to better understand viral pathogenesis. He has been studying HIV interactions with host factors since 2000 when he was a postdoctoral researcher. During the last eight years of m independent HIV research, Dr. Li has focused on the molecular mechanisms of dendritic cell-mediated HIV transmission and HIV restriction in human myeloid cells. Dr. Li also established a productive research record in this area. 

Dr. Li Wu joined the Department of Veterinary Biosciences at The Ohio State University (OSU) as a tenured Associate Professor on October 1, 2009. Dr. Li appointment is approximately 80% on research and he also devoted his effort to teaching and service. 

 Biography
Research Interest :

Dr. Li Wu current research focuses on the molecular and cellular mechanisms of HIV restriction in human myeloid cells mediated by the host protein SAMHD1. These studies can facilitate our understanding of HIV pathogenesis and the development of more effective interventions against HIV infection and AIDS. Since 2012, in collaboration with two physician scientists at OSU, he has expanded his research to cancer biology, which focuses on the novel role of SAMHD1 as a tumor suppressor in cutaneous T-cell lymphomas.

 Research Interest
Nafees Ahmad

Nafees Ahmad
Immunobiology Department
University of Arizona, USA

Biography :

Dr. Nafees Ahmad is Professor of Immunobiology and Director of Immunity and Infection at the College of Medicine, University of Arizona in Tucson, Arizona. He obtained his undergraduate and postgraduate education from the Aligarh Muslim University, India and doctorate from the Central Drug Research Institute, Lucknow and Aligarh Muslim University, India. He completed his postdoctoral fellowship in HIV/AIDS from the National Institutes of Health, Bethesda, Maryland, USA. His research has focused on mechanisms of HIV immunopathogenesis in younger and older HIV-infected patients, including the aging of the immune system. We are investigating the mechanisms of differential HIV-1 infection in younger and older populations, including the role of viral and host factors and dysregulation of T cell functions. These viral, host and immune factors may be targeted for developing new strategies for treatment and prevention of HIV infection

 Biography
Research Interest :

HIV-1 infection in younger and older populations, including the role of viral and host factors and dysregulation of T cell functions

 Research Interest
Severin O. Gudima

Severin O. Gudima, PhD
Microbiology, Molecular Genetics and Immunology
University of Kansas, USA

Biography :
 Biography
Research Interest :

The research in my laboratory is aimed to ascertain molecular mechanism of HBV/HDV infection with emphasis on pathogenesis. The goal of the first ongoing study is to understand how the virus-induced pathogenesis is linked to a particular genotype of HBV. Data available strongly indicate that infection with different HBV genotypes can lead to substantially different levels of liver damage and corresponding progression of the disease. We plan to compare aspects of replication, assembly, and also infectivity in primary human hepatocytes (PHH) and certain determinants of the host response for all known 8 HBV genotypes. The finding of the most infectious HBV genotype will be of significant importance to the HBV field. It has a great potential for three major applications. The peptides derived from the N-terminus of the PreS1 domain of the large envelope protein, which belongs to the more infectious genotype, would be more potent antiviral inhibitors, more efficiently interacting with the receptor(s) and preventing HBV and HDV spread. If the more infectious genotype displayed the ability to infect the majority of PHH, than it would be possible to conduct the microarray studies using the in vitro infection system of PHH and examine the host response. Such studies now are not feasible, since currently in a best situation only about 20% of hepatocytes can be infected. The use of the more infectious HBV genotype can also result in the establishment of HBV-susceptible cell lines. This will seriously reduce the need for primary human hepatocytes, which so far represent the most adequate cells susceptible to HBV infection. Overall, this study will: (i) facilitate the understanding of the molecular mechanism of HBV genotype-specific pathogenesis; (ii) have a serious impact on the understanding of virus-host interactions; (iii) have the potential to advance the development of new generation of anti-HBV antiviral peptides.

 Research Interest
Slobodan Paessler

Slobodan Paessler, PhD
Department of Pathology
University of Texas Medical Branch, USA

Biography :

Dr. Slobodan Paessler is working as professor in Department of Pathology at University of Texas Medical Branch. Dr. Paessler obtained his medicine degree in Veterinary Medicine from LMU Munich and Doctorate in Experimental Pathology from University of Texas Medical Branch at Galveston, USA.

 Biography
Research Interest :

Dr. Slobodan Paessler research interest is in understanding the mechanisms by which emerging RNA viruses cause encephalitis, hemorrhagic fever, or respiratory diseases, molecular biology, viral pathogenesis, vaccine/antivirals, and diagnostics development. The main research in Dr. Paessler lab has focused on viral pathogenesis, vaccine development and on development of animal models to test new vaccine candidates and antiviral drugs. We seek to elucidate the nature of the neuroinflammatory response to CNS invasion by viruses in diverse families such as Togaviridae, Orthomyxoviridae, Bunyaviridae and Arenaviridae. Our approach is designed to provide expertise for the development and evaluation of vaccines and anti-viral drugs in collaboration with partners in academia (within and between institutions), in biotechnology, and in federal agencies

 Research Interest
Jared D Evans

Jared D. Evans, PhD
Molecular Microbiology and Genetics
University of Pittsburgh, USA

Biography :

Jared D. Evans obtained his B.S. in Biology at The College of New Jersey in 1997. He was awarded the Ph.D. in Molecular Microbiology at Stony Brook University in 2002 after completing thesis research on Adenovirus replication and its reorganization of important subnuclear organelles under the guidance of Dr. Patrick Hearing.

Dr. Evans was a post-doctoral fellow at The Salk Institute for Biological Sciences with Dr. John A. T. Young where is helped develop and validate a cell-free system for retroviral entry. In 2004, he joined the laboratory of Dr. Christoph Seeger at Fox Chase Cancer Center. As a post-doctoral fellow, he developed a program to study medically importantflaviviruses (West Nile and dengue virus) and their interaction with the innate immune signaling pathway. In 2008, he was appointed Assistant Professor in the Center for Vaccine Research and Department of Molecular Microbiology and Genetics at the University of Pittsburgh.

 Biography
Research Interest :

Dr. Evans works in collaboration with colleagues and post-doctoral fellows to understand complex mechanisms in virus-host interactions with goals toward vaccine development. His main focus is investigating the role of West Nile and dengue virus proteins in abrogating the response to the antiviral innate immune molecule Interferon. By understanding how these viruses resist antiviral environments, more effective rationally designed therapeutics and live-attenuated vaccines can be produced. Dr. Evans has also expanded his vaccine research efforts to include the development of virus-like particle formulations derived from a novel yeast platform.

 Research Interest
Luis Martinez-Sobrido

Luis Martinez-Sobrido, PhD
Department of Microbiology and Immunology
University of Rochester Medical Center, USA

Biography :

Dr. Martinez-Sobrido obtained his B.S. in Biological Sciences at Universidad de Navarra in Pamplona (Spain). Dr. Martinez-Sobrido was awarded the Ph.D. in Virology and Molecular Biology at Universidad Autonoma de Madrid (Spain). Dr. Martinez-Sobrido received his post-doctoral training at Mound Sinai School of Medicine in New York (USA). In 2008 Dr. Martinez-Sobrido was appointed Assistant Professor in the Department of Microbiology and Immunology at University of Rochester Medical Center in New York (USA). Currently, Dr. Martinez-Sobrido is Associate Professor in the Department of Microbiology and Immunology at University of Rochester Medical Center in New York (USA) and External Professor at the Universidad Autonoma de Yucatan in Merida (Mexico).

 Biography
Research Interest :

Dr. Martinez-Sobrido’s research interest has been focused on the molecular biology, immunology, and pathogenesis of negative-stranded (Influenza viruses, Respiratory Syncytial Virus, Human Metapneumovirus, arenavirus, Thogoto virus, Ebola virus, Crimean Congo Hemorrhagic Fever virus) and positive-stranded (Dengue virus, SARS coronavirus, Mouse Hepatitis virus) RNA and DNA (vaccinia) viruses.

Dr. Martinez-Sobrido has extensive knowledge in the reverse genetics techniques for rescuing RNA viruses, pioneered the development of techniques and screening assays to identify viral-encoded interferon antagonist proteins, and established new molecular biology approaches to study highly pathogenic viruses without the requirement of special biosafety conditions. Dr. Martinez-Sobrido contributions to the infectious disease field include, among others, 1) plasmid-based reverse genetics techniques to genetically manipulate RNA viruses that have been used to examine virus-host interactions and the development of vaccines; 2) plasmid, virus and cellular based assays for the identification of virus-encoded interferon-antagonist proteins that have been used to uncover molecular mechanisms involved in viral pathogenesis; and, 3) single-cycle infectious influenza and arenaviruses to study highly pathogenic members in these virus families without the requirement of special biosafety conditions. Dr. Martinez-Sobrido current research focuses on understanding the molecular determinants of viral pathogenesis, how viruses interact with their hosts, and to identify new antivirals and vaccines to prevent viral infections.

 Research Interest
Maria Antonieta Guerrero-Plata

Maria Antonieta Guerrero-Plata, PhD
Department of Pathobiological Sciences
Louisiana State University, USA

Biography :

Dr. Guerrero-Plata received her undergraduate degree from Universidad Autonoma de Tamaulipas in Reynosa, Mexico. She then traveled to Mexico City to pursue her graduate education where she obtained her MSc and PhD from the Universidad Nacional Autonoma de Mexico (UNAM). Additional training at CINVESTAV and Imperial College London, U.K. honed her knowledge and research skills in the field of respiratory medicine and viral immunology. Dr. Guerrero-Plata acquired further research training as postdoctoral fellow at the University of Texas Medical Branch (UTMB) at Galveston where she also was a McLaughlin Fellow. Dr. Guerrero-Plata was appointed an instructor in the department of Pediatrics upon the completion of her fellowship, and became an assistant professor in the same department after obtaining extramural funding as principal investigator. Dr. Guerrero-Plata joined the Department of Pathobiological Sciences, Louisiana State University in 2009

 Biography
Research Interest :

Dr. Guerrero-Plata’s research interests are in the field of viral immunology focused on innate immunity, dendritic cells and respiratory viruses. Her work includes the study of the immune response to respiratory syncytial virus and human metapneumovirus, the most important cause of lower respiratory tract infections in children, elderly and immunocompromised patients. The long-term goal of her research is to develop new strategies to boost antiviral immunity and long-lasting protection against respiratory viral pathogens that cause significant airway morbidity. Additional studies in her laboratory are directed to determine the mechanisms by which environmental factors alter the frequency and severity of respiratory viral infections

 Research Interest
Jennifer Webster-Cyriaque

Jennifer Webster-Cyriaque, PhD
Department of Microbiology and Immunology
University of North Carolina, USA

Biography :
 Biography
Research Interest :

A goal of our laboratory is to understand viral molecular pathogenesis in oral disease, in states of health and immunocompromise. There are eight known human herpes viruses that cause persistent infections and are shed into the oral cavity during immunosuppression causing increased morbidity. These DNA viruses are all marked by their ability to establish permanent, persistent infections where the viral infection may be latent, chronic, or transforming. These viruses manipulate host immune recognition and response to allow for these continuous infections and affect specific cellular pathways to induce cell growth or death. Our laboratory seeks to understand the critical molecular interactions that occur between the virus and the host that govern the development of oral lesions and malignancies.

These viruses cause AIDS defining lesions such as Kaposi's Sarcoma, Hairy leukoplakia (HLP) and Herpes Simplex Virus (HSV)-associated ulcerative disease. Over time there has been a shift in the prevalence of these lesions with the incidence of Hairy Leukoplakia, and Kaposi's Sarcoma decreasing and HIV associated Salivary Gland disease (HIV SGD) on the rise. Past and ongoing studies have determined viral and cellular gene expression within the HLP and oral KS lesions. An aim of the laboratory is to determine whether viral prevalence varies with changes in immune status and anti-AIDS drug regimen. We are developing technologies to characterize viral infection and load in body fluids and oral lesions. In HIV SGD, the etiologic agent remains unknown. One goal of the laboratory is to characterize pathogenesis in HIVSGD and determine the role of candidate herpes viruses in this disease. Current projects include determination of differential gene expression in diseased versus healthy glandular tissue.

 Research Interest
Kristine Yoder

Kristine Yoder, PhD
Molecular Virology, Immunology, and Medical Genetics
Ohio State University Wexner Medical Center, USA

Biography :
 Biography
Research Interest :

Integration of the retroviral genome into a host chromosome is an essential part of the HIV life cycle. However, understanding of integration is still incomplete. Our studies of host DNA repair factors have identified both positive and negative regulators of retroviral infection. Proteins of the nucleotide excision repair pathway, XPB and XPD, are able to defend the host genome from retroviral integration by degrading the viral cDNA by an evolutionarily ancient mechanism. In contrast, base excision repair (BER) proteins enhance HIV integration. We are continuing to explore the role of BER proteins during integration. Finally, we are evaluating the role of chromatin during integration. Integrase favors DNA wrapped around nucleosomes far more than naked DNA. These studies provide fundamental knowledge of integration that may be useful for enhancing anti-retroviral therapy and also for targeting integration of retroviral gene therapy vectors.

 Research Interest
Fanxiu Zhu

Fanxiu Zhu, PhD
Department of Biological Sciences
Florida State University, USA

Biography :

Fanxiu Zhu studies includes Kaposi’s sarcoma–associated herpesvirus (KSHV), a human DNA tumor virus associated with several human malignancies, including Kaposi’s sarcoma, primary effusion lymphoma, and multicentric Castleman’s disease. I am interested in viral proteins that are localized in the tegument layer, a space between capsid and envelope in the virus particle. The tegument comprises at least a dozen proteins that are delivered into cells upon infection, so they have the opportunity to exert their functions at the very beginning in the infection process. The unique temporal and spatial expressions of tegument proteins put them in the forefront of coping with the host cellular environment. We discovered that KSHV tegument protein ORF45 interacts with interferon regulatory factor 7 (IRF-7) and antagonizes host antiviral response. Recently, we found that ORF45 also interacts with p90 ribosomal S6 kinases (RSKs) and modulates the ERK/RSK MAPK signaling pathway, which plays critical roles in KSHV lytic replication. We are now exploring the mechanisms by which ORF45 evades innate immune response and modulates ERK/RSK signaling. We are also interested in the structural analysis of herpesvirus tegument by cryoEM. The structural organization and morphogenesis of herpesviral tegument are largely unknown. We use various approaches to investigate why and how viral proteins are selectively assembled into the tegumen

 Biography
Research Interest :
 Research Interest
Wenzhe Ho

Wenzhe Ho, MD
Department of Pathology and Laboratory Medicine
Temple University School of Medicine, USA

Biography :

Dr. Wen-Zhe Ho is a Tenure Professor at the Department of Pathology and Laboratory Medicine, Temple University School of Medicine and Director of Center for Animal Experiment/ABSL III Lab, Professor of Key Laboratory of Virology , Wuhan University School of Medicine. Dr. Ho received his medical, research and public health training at the Wuhan University School of Medicine in China and the University of Pennsylvania School of Medicine. Since 1993 he served on the faculty of the University of Pennsylvania School of Medicine until joining the Temple University School of Medicine in September, 2009. Dr. Ho also serves as Editor in Chief of Virology: Research and Treatement, a member of editorial board of J. NeuroVirology, J. NeuroImmune Pharmacology, and Chinese J. Pediatrics (International Edition). Dr. Ho’s research work has produced over 110 peer-reviewed articles and 18 editorials, reviews and chapters. Some of his publications appear in the highly regarded journals including PNAS, Blood, Hepatology, J. Virology, J. Immunology, J. Infect Dis., and American J. Pathol.

 Biography
Research Interest :

Dr Ho is a viral immunologist with a research interest in how the body protects itself against viral infections, particularly human immunodeficiency virus (HIV) and HIV and/or HCV diseases. The work in the Ho laboratory is focused on virus-host interactions that govern innate immune response and viral replication within a target cell. One question that is interesting to the Ho laboratory is how HIV /HCV escape from host defense mechanisms, resulting in persistent infection.

 Research Interest
Jian Zhu

Jian Zhu, PhD
Microbiology and Immunology
University of Rochester, USA

Biography :

Dr. Zhu obtained his Bachelor of Science in Pharmacology from Peking University in China. He did his Ph.D. in Pharmacology with Drs. Heng Zhu and Diane Hayward at the Johns Hopkins University School of Medicine. Then he completed his postdoctoral fellowship with Dr. Stephen Elledge at Brigham and Women’s Hospital of Harvard Medical School. Dr. Zhu joined the University of Rochester Medical Center (URMC) as an Assistant Professor of Microbiology and Immunology (primary) and Biochemistry and Biophysics (secondary).

 Biography
Research Interest :

Dr. Zhu’s lab studies the host-virus interactions, particularly for HIV and herpesviruses, by using recently developed, multidisciplinary systematic approaches, and work at the interface of virology, immunology, proteomics, and functional genomics. The goal is to construct a global landscape of gene network modulating viral infection by integrating multiple systematic approaches and further study key genes that play a role in viral replication or host antiviral defense using cell and/or animal models and multiple skills including biochemistry and biophysics.

 Research Interest
Sita Awasthi

Sita Awasthi, PhD
Infectious Disease Division, Department of Medicine
University of Pennsylvania, USA

Biography :

Sita Awasthi is a Research Assistant Professor in the Department of Medicine Infectious Disease Division at University of Pennsylvania, Philadelphia PA, USA. She earned her PhD from Devi Ahilya University Indore, India. She has published over 20 peer reviewed papers and was co-author of book chapters and reports. She was the President of Association of Women in Science AWIS Philadelphia chapter. She is an active member of International Society of Vaccines. She has served as a reviewer of peer reviewed journals in the area of vaccine and virology.

 Biography
Research Interest :

Vaccine development against infectious disease in general, Pre-clinical development of vaccine against HSV-2 and HSV-1, Spread and pathogenesis of HSV-1/HSV-2, Evasion of host immunity by viruses, HSV-2-HIV co-infection.

 Research Interest
Kevin Coombs

Kevin Coombs, PhD
University of Manitoba, Canada

Biography :

Dr. Kevin Coombs obtained his BA degrees in Biology and English from the State University of New York in Geneseo, NY, and his PhD degree in Microbiology from the University of Texas at Austin in 1986. After post-doctoral work at Harvard Medical School, he joined the faculty at the University of Manitoba in 1990. He is currently a Professor in the Department of Medical Microbiology, with cross-appointments in the Department of Physiology, the Department of Microbiology/Faculty of Science, and the Manitoba Institute of Child Health.

Dr. Kevin Coombs obtained his BA degrees in Biology and English from the State University of New York in Geneseo, NY, and his PhD degree in Microbiology from the University of Texas at Austin in 1986. After post-doctoral work at Harvard Medical School, he joined the faculty at the University of Manitoba in 1990. He is currently a Professor in the Department of Medical Microbiology, with cross-appointments in the Department of Physiology, the Department of Microbiology/Faculty of Science, and the Manitoba Institute of Child Health.

 Biography
Research Interest :

Dr. Coombs’ major research interests are to delineate the protein and nucleic acid interactions in nucleoprotein complexes, using a variety of RNA viruses as models. His lab studies how these interactions change as a result of, and in turn, are modulated by, conformational transitions that occur during macromolecular assembly and disassembly, how these processes can be attenuated by anti-viral compounds, and how these processes in virus infections contribute to pathogenesis in the host. This work, which has been continuously funded by the MRC/CIHR since the year after he moved to Manitoba, is in general areas of:

  • Generation and molecular characterization of assembly-defective virus mutants
  • Inhibition of virus replication using pharmacologic inhibitors
  • Mass spectrometry- and Systems-based analyses of virus and host protein alterations
  • Molecular characterization of RNA-dependent RNA polymerases and cofactor proteins
 Research Interest
Weiming Yuan

Weiming Yuan, PhD
Department of Molecular Microbiology and Immunology
University of Southern California, USA

Biography :

Dr. Weiming Yuan is an assistant professor working on molecular virology and viral immunology in the Department of Molecular Microbiology and Immunology at the University of Southern California in Loas Angeles, California. He received his Ph.D. degree in Molecular Virology at the University of Texas at Austin, specifically working on the virus-host interaction during influenza pathogenesis. He then had postdoctoral training in the Department of Immunobiology at Yale University School of Medicine where he initiated the work on the molecular mechanism and viral modulation of CD1d antigen presentation pathway. He is a member of American Society for Microbiology, American Society for Virology and American Association of Immunologists.

 Biography
Research Interest :

Dr. Weiming Yuan research interests include Virology, Immunology, Viral pathogenesis, Viral immune evasion, Infectious dieases, Herpes viruses, Influenza viruses

 Research Interest
Junji Xing

Junji Xing
Cornell University,USA

Biography :

Dr. Junji Xing received his Ph.D. at Wuhan Institute of Virology, Chinese Academy of Sciences. During his Ph.D. studies, his research focuses on elucidating the molecular mechanism of host innate immune evasion by herpes simplex virus type 1 (HSV-1), interactions between virus and host cells, subcellular transport mechanism of viral proteins in host cells. As a postdoc associate in University of Minnesota, he investigated the mechanisms of immune suppression and pathogenesis by Arenaviruses in human primary cells or guinea pig animal model. As a research associate in Houston Methodist Research Institute affiliated with Weill Cornell Medicine of Cornell University, his research is now involved in characterizing the roles of TRIM family protein in host innate immunity regulation

 Biography
Research Interest :

Innate immune response and virus infection; Virus-Host Interactions; Pathogenesis and immunities of virus infection; Subcellular transport mechanism of viral proteins; Vaccine and antiviral treatment.

 Research Interest
Tomy Joseph

Tomy Joseph, PhD
Faculty of Medicine
University of Manitoba, Canada

Biography :

Tomy Joseph working as Assistant Professor of Medical Microbiology, College of Medicine, University of Manitob. He completed his Postdoctoral Fellowship from National Institutes of Health, USA

 Biography
Research Interest :

Diagnostic virology. Monitoring emergence of zoonotic viruses especially new avian and swine influenza viruses and foreign animal disease viruses. Molecular basis of viral pathogenesi

 Research Interest
Sean Li

Sean (Xuguang) Li, PhD
Department of Biochemistry, Microbiology, and Immunology
University of Ottawa, Canada

Biography :

Dr. Sean (Xuguang) Li received his medical training in Suzhou, China, followed by a graduate study training period in medical research in Beijing. In 1996 he obtained his PhD from McGill University under the supervision of Prof Mark Wainberg. From 1996 to 2000, he was a Research Fellow at the Dana Farber Cancer Institute/Harvard Medical School with Dr. Wayne Marasco. Currently, Dr. Li is a Senior Scientist at Health Canada, while serving as an Adjunct Professor at BMI and a member of Faculty of the Graduate and Postdoctoral Studies, University of Ottawa.

 Biography
Research Interest :

Dr. Sean (Xuguang) Li research interests are Gene Therapy, Biotherapeutics, Molecular and Immunological Studies on Viruses of Medical Importance, Antiviral, Vaccine Research and Antibody Engineering. Conducting regulatory research on quality control methodologies for vaccines and biotherapeutics. Investigation of potential adverse reactions associated with vaccine vectors. Determination of biomarkers for the analyses of immune responses to vaccines.

 Research Interest
Pam Vallely

Pam Vallely, PhD
Microbiology and Virology Unit
University of Manchester, UK

Biography :

2005- 2012 Senior Lecturer in Medical Virology
1991-2005 Lecturer in Medical Virology, University of Manchester
1988-1991 Clinical Scientist (Grade B), Department of Haematology, Manchester Royal Infirmary.
1987-1988 Post Doctoral Research Assistant, Department of Virology, University of Sheffield

 Biography
Research Interest :

Pam Vallely research interest is in viral infection of the central nervous system, particularly in exploring novel or unrecognised causes of viral encephalitis and improving diagnosis of these. Dr. Vallely also interested in infectious causes of hearing loss, particularly congenital cytomegalovirus infection.

 Research Interest
Mike Griffiths

Mike Griffiths, PhD
Clinical Infection, Microbiology and Immunology
University of Liverpool, UK

Biography :

Dr. Mike Griffiths is working as Clinical Lecturer in the Brain Infection Group, Institute of Infection and Global Health, University of Liverpool. The groups main aim is to improve diagnosis, treatment and management of brain infections in the UK and world-wide.

 Biography
Research Interest :

Dr. Griffiths research Interests lie in the host responses to severe infection, particularly neurological infectious insults, with a focus on identifying diagnostic and prognostic markers as well as to better understand the role of host and pathogen responses in determining the outcome of brain infections. I use transcriptomic and proteomic approaches to explore these responses, both in patient populations and human brain infection models. In previously trained in Oxford, Kenya (Kilifi) and Stanford, and I maintain collaborations with these Institutes. My clinical training is paediatric and adult neurology.

 Research Interest
Polly Roy

Polly Roy, PhD
Department of Infectious and Tropical Diseases
London School of Hygiene & Tropical Medicine, UK

Biography :

Polly Roy began her education in Calcutta, India but won a fellowship to NYU for her PhD under the supervision of the molecular biologist, Sol Spiegleman. A 3-year postdoctoral position in RNA virology at the Waksman Institute, Rutgers University, followed after which she joined the University of Alabama at Birmingham to establish her own Bluetongue virus research group with funds from NIH, NSF and USDA. In 1985 she became a Professor at UAB in 1985. In 1987 she received a senior International Fogarty fellowship to study at the University of Oxford where she gradually established a UK-based research group. In 1997, she became Professor at the University of Oxford and in 2001 took the chair of Virology at the London School of Hygiene and Tropical Medicine. Her studies have contributed in many areas of virology, notably virus structure, assembly, RNA replication and virus release. She has supervised over 140 post-doctoral and post-graduate researchers, published over 290 research papers and has served on various International scientific organisations, committees and boards. She has organized several highly successful international conferences, particularly on the subject of virus assembly and in 2006 was elected a Fellow of the Academy of Medical Sciences.

 Biography
Research Interest :

Roy’s salient contribution has been the first complete molecular understanding of a distinct group of viruses, orbiviruses, of serious health and economic impact. Roy used multi-disciplinary approaches to provide a detailed understanding of a complex double -stranded RNA virus, Bluetongue virus (BTV), a member of the Reoviridae (one of the largest RNA virus family) and a modelsystem for a number of similar viruses that are pathogenic to human and animal (e.g. Rotaviruses). Polly Roy research interests include RNA virology, Viral genetics, Protein function and capsid assembly, Replication of segmented genome and packaging, Virus trafficking in the host cell, Technology development and the generation of particulate vaccines

 Research Interest
Muhammed Babakir-Mina

Muhammed Babakir-Mina, PhD
University Tor Vergata, Italy

Biography :

Muhammed Babakir-Mina holds PhD in Medical Microbiology and Immunology from Sulaimani Polytechnic University, Sulaimani Governorate

 Biography
Research Interest :

Medical Microbiology and Immunology

 Research Interest
 Acceptance Letter
Greg Moseley

Greg Moseley, PhD
Department of Biochemistry and Molecular Biology
The University of Melbourne, Australia

Biography :

Following his PhD research at the University of Sheffield (UK) and WEHI (Australia), Dr Moseley was awarded a Royal Society fellowship to undertake post-doctoral research in Australia where he now heads a research team at Monash University, focussed on understanding the pathogenic mechanisms of lyssaviruses including rabies, and paramyxoviruses including Nipah. His principle research interest is the role of viral protein subcellular trafficking in immune evasion, and his main research findings in this area have included the first demonstrations of a role for microtubules in viral immune evasion, and of the importance of viral protein trafficking to virulence in vivo.

 Biography
Research Interest :

Dr. Moseley research interests includes Rabies, Australian bat lyssavirus Nipah/Hendra Interferon Innate immunity Viral immune evasion

 Research Interest
Yuxian He

Yuxian He, PhD
Chinese Academy of Sciences, China

Biography :
 Biography
Research Interest :

Molecular mechanism of HIV infection and host immune responses. Development of antiviral neutralizing antibodies, vaccines and therapeutics

 Research Interest
Yuan Zhi-ming

Yuan Zhi-ming, PhD
Chinese Academy of Sciences, China

Biography :

Yuan Zhiming obtained his Ph.D. in microbiology and biotechnology at Sun Yat-sen University, and then trained and worked in France, Denmark, and United States for several years. He has been working as Deputy Director and Professor at the Wuhan Institute of Virology, Chinese Academy of Sciences since 2000. As a principal investigator, his research group works on the diagnosis and drug discovery of aborviruses, genomics, insecticidal proteins and their mode of action, genetic modification of entomopathogenic bacteria (Bacillus spp), as well as the production, standardization and application of bio-pesticide and other microbial agents. Since 2003, he was appointed the chairman of Institutional Biosafety Committee, member of National Laboratory Biosafety Committee, advisor of different national technical committees on biosafety management, general manager of National High-Level Biosafety Laboratory in Wuhan. He also works as a group leader on the Sino-French biosafety legislation cooperation. In addition, he was elected as President of Hubei Society for Microbiology in 2008

 Biography
Research Interest :

Microbiology,Biotechnology and Virology

 Research Interest
Paulo Gouveia de Almeida

Paulo Gouveia de Almeida, PhD
Institute of Hygiene and Tropical Medicine
Universidade Nova de Lisboa ,Portugal

Biography :

A. Paulo G. de Almeida is Associate Professor in Medical Entomology/Parasitology, at the Institute of Hygiene and Tropical Medicine, Universidade Nova de Lisboa (IHMT/UNL), Portugal since 2009.

 Biography
Research Interest :

Medical Entomology and Parasitology. Mosquitoes, ticks, arbovirus, WNV, malaria, filariasis, climate changes.

 Research Interest
Chen Xinwen

Chen Xinwen, PhD
Wuhan Institute of Virology
Chinese Academy of Sciences, China

Biography :

Xinwen CHEN, PhD,, Professor. He obtained his BSc and MSc from the Department of Biology, Central China Normal University in 1986 and Henan University of Technology in 1988, respectively. In 1998, he obtained his PhD from Wageningen University in 2001. He subsequently worked at the University of California at Berkeley and Wageningen University as a visiting scientist. Dr. Chen is one of the scientists in “Hundred-talent Project” CAS and one of the awardees of the "National Outstanding Youth Fund". Dr. Chen’s current positions include Director General of WIV, a member of the institute’s Academic Committee, a member of the institute's Academic Degree Committee. In addition, Dr. Chen is Editor- in-Chef of Virologica Sinica, a member of the Council of the Hubei Society of Microbiology and a member of the Council of the Hubei Society of Biotechnology. Dr. Chen as the chief scientists assume "national major scientific research projects", and also assume multiple projects such as 973, the national natural science foundation and institute project. Dr. Chen has more than 130 publications, of which more than 70 are registered in the SCI index. He was also awarded second prize in the "National Innovation Award" in 2005, awarded first prize in the "Natural Science of Hubei Province" in 2011.

 Biography
Research Interest :

Virology

 Research Interest
Guillermo H  Sguazza

Guillermo H Sguazza PhD
Department of Microbiology
National University of La Plata, Argertina 

Biography :

I have a degree of Bachelor in biotechnology at the National University of Quilmes, Argentina; oriented to the knowledge about molecular biology techniques applied to different systems of proteins expression, genetic engineering techniques and the development of biotechnology processes. I hold a Ph.D. in Veterinary Sciences at the National University of La Plata, Argentina; my doctoral thesis was focused on the expression of recombinant proteins of Equine Influenza virus. This expanded my knowledge in the development, production and quality-control of recombinant proteins. At Present, I work as teacher and researcher at the Chair of virology in the Department of Microbiology of the Faculty of Veterinary Science at the National University of La Plata, Argentina. My areas of expertise include virology, Influenza A virus, diagnostic techniques, molecular biology, cloning and expression of proteins. My current research includes expression of recombinant proteins (Equine Influenza, Rabies and Canine Distemper virus); and the diagnostic and epidemiology of bee viruses.

 Biography
Research Interest :

Virology, Influenza A virus, diagnostic techniques, molecular biology, cloning and expression of proteins

 Research Interest
 Acceptance Letter
Mahmoud Reza Pourkarim

Mahmoud Reza Pourkarim, PhD
Microbiology and Immunology
Rega Institute for Medical Research,Belgium

Biography :

MahmoudReza Pourkarim has completed his PhD in 2012 from Katholieke University of Leuven, Belgium. He awarded postdoctoral grant of FWO. He works as a senior researcher in Hepatitis B Virus group, at the Clinical and Epidemiology Virology Laboratory.

 Biography
Research Interest :

Hepatitis B Virus

 Research Interest
Jose Manuel Grijalva Chon

Jose Manuel Grijalva Chon, PhD
University of Sonora ,Mexico

Biography :

Dr. Grijalva-Chon obtained his B.S. in Oceanology at Autonomous University of Baja California (Mexico) and awarded the M.S. and Ph.D. in Oceanology-Marine Ecology at Center of Scientific Research and Higher Education of Ensenada (Mexico). He was a Visiting Professor in the Ocean Research Institute at University of Tokyo in 1992. He is currently a Professor-Researcher in the Department of Scientific and Technological Research at University of Sonora (Mexico) since 1986. He has published 30 peer reviewed papers

 Biography
Research Interest :

Together with colleagues and students, Dr. Grijalva-Chon is interested in studying host-pathogen interactions under different environmental conditions on species used in aquaculture such as shrimp and mollusks. Also, it is of interest to him the study of genomic variants and their relationship to the infective potential

 Research Interest
 Acceptance Letter
 
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