University of Southern California
Alexander M. Klibanov
Massachusetts Institute of Technology
Daniel L. Kaplan
Florida State University
John D. Shaughnessy
Icahn School of Medicine
Archives of Medical Biotechnology is a multidisciplinary, open access, peer-reviewed, scientific journal that focusses on the publication of scientific manuscripts pertaining to avant-gardemedical biotechnological research studies. Medical biotechnology involves congregation ofbasic concepts in cell biology, microbiology, molecular biology and bioinformatics for the development of cutting edge pharmaceutical agents. The medical biotechnology research findings ameliorate the process of development of novel diagnostic and therapeutic tools for the detection and treatment of acute and chronic diseases.
Archives of Medical Biotechnology journal strives for the wide spread promulgation of manuscripts related to recent developments in the field of applied medical sciences.The journal is an excellent rostrum for showcasing advanced medical research innovations pertaining to the development of advanced tools and techniques for medical and pharmaceutical applications viz. prosthetics limbs, portable dialysis machine, muscle stimulators, nerve regenerators, absorbable heart stent, contact lenses, diagnostic tool kits etc.
The foremost objective of the journal is to augment the furtherance of medical biotechnological research and development of novel biomedical principles, methods, tools and techniques with direct or indirect biomedical implications. The journal maintains exemplary standards regarding the originality and clinical importance of the accepted manuscripts. The worldwide dispersal of the published articles enhances their scientific impact and practical applicability.
Biotechnology deals with cellular and molecular process to develop technologies that helps to modify the way of living. It is also defined as the proper use of living organism, cells and cellular components for the genetic development of living things which is helpful for man.
Medical biotechnology also called as red biotechnology is the use of organisms and organisms-isolated materials for research and to produce diagnostic and therapeutic products that help to treat and prevent human diseases. The aim of medical biotechnology is the Prevention, Diagnosis and Treatment of diseases. The principles of medical biotechnology are applied in pharmacology, gene therapy, stem cells and tissue engineering. Medical biotechnology is a rapidly evolving field integrating knowledge obtained in molecular, cell biological, genetic and immunological scientific areas.
A genome is the total set of genetic information in an organism. It provides the information for organism’s function. In living organisms, the genome is stored in long molecules of DNA known as chromosomes. Small sections of DNA, called genes, code for the RNA and protein molecules required by organism. In eukaryotes, each cell's genome contains within a membrane-bound structure called the nucleus. Prokaryotes, doesn’t contain inner membranes, store their genome in a region of the cytoplasm called the nucleoid. Transcriptome is the full range of RNA molecules expressed by a genome, and the variety of proteins produced by the genome is called its proteome.
Human Genetics is the branch of science concerned with genes, genetic variation and heredity in living organisms and genetic aspects of humans as a species. Genetic information is the information about an individual’s genetic tests and the genetic tests of an individual’s family members, as well as information about the disease or disorder in an individual’s family members. Family medical history is also important because it is often used to determine whether someone has an increased risk of getting a disease, disorder, or condition in the future. Progress in molecular biology has clarified the molecular structure of chromosomes and their constituent genes and the ways in which change in the molecular structure of a gene helps to overcome a disease. The genetic information of the developing human is stored in coded form within molecules of DNA (deoxyribonucleic acid). DNA is composed of a chain like arrangement of smaller molecules known as nucleotides, which forms a code that contains information and it defines the structure of various protein molecules.
Gene is responsible for all the physical & mental characteristics which carries out from one generation to other. Gene therapy is a technique for the correction of defective genes, it involves by inserting one or more corrective genes that have been designed in laboratory, into the genetic material of a patient's cells to overcome a genetic disorder.
Different individuals react differently to the same drug or treatment, so the vision of pharmacogenomics is to be able to design and produce drugs that are adapted to each person’s genetic factor. The purpose of pharmacogenomic testing is to figure out if a medication is right for an individual human. A small blood or saliva sample can help to determine whether a medication may be an effective treatment for a human, what is the best dose of a medication for a patient, whether a human could have serious side effects from a medication or not.
In modern medicine industry biopharmaceutical technique poses one third of the manufacturing process. In this process the drugs are produced by following the biotechnological method like genetic engineering, Recombinant DNA technology gene transfer& antibody production method. Biopharmaceutical Drug is a protein molecule which derived from living organism cell. Biopharmaceutical drugs are used to fight cancer, diabetes, hepatitis, viral infections, etc.
Molecular medicine is a branch of medicine that develops the ways to diagnose and treat disease by understanding the way genes, proteins and other cellular molecules work. It is based on research that shows how certain genes, molecules, and cellular functions may become abnormal in diseases such as cancer.
Stem cell research have a contribution as a central role in regenerative medicine, which also spans the disciplines of tissue engineering, cellular therapeutics, gene therapy, developmental cell biology, biomaterials, chemical biology and nanotechnology. Stem cells have remarkable potentials to develop into different types of cell in the body during early life and growth. In many tissues stem cell act as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive.
Bioassay is a technique for the determination of concentration, purity, and/or biological activity of a substance like vitamin, hormone, plant growth factor, antibiotic, enzyme. The aim of most bioassays is to perform a dilution assay, which measures the biological responses at several doses. Prediction of a dilution assay is that the active component follows the same principle of activity in standard and sample preparation.