Review Article, J Otol Rhinol Vol: 4 Issue: 6
Genetic Aspects of Allergic Rhinoconjunctivitis: A Review
| Arzu Didem Yalcin1*, Emre Ozkan2, Fusun Uzunoglu3 and Kemal Kiraz4 | |
| 1Department of Allergy and Clinical Immunology, Antalya, Turkey | |
| 2Anatolia Hospital Department of Pulmonary Medicine, Antalya, Turkey | |
| 3Dunya Goz Hastanesi Department of Ophthalmology, Istanbul, Turkey | |
| 4Antalya Education and Training Hospital, Department of Pulmonary Medicine, Antalya, Turkey | |
| Corresponding author : Dr. Arzu Didem Yalcin, MD Internal Medicine, Allergy and Clinical Immunology, Genomics Research Center, Academia Sinica,11529, Taiwan and Antalya Education and Training Hospital. Department of Allergy and Clinical Immunology, 07070, Antalya, Turkey E-mail: adidyal@yahoo.com/adidyal@gate.sinica.edu.tw |
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| Received: September 05, 2015 Accepted: November 05, 2015 Published: November 09, 2015 | |
| Citation: Yalcin AD, Ozkan E, Uzunoglu F, Kiraz K (2015) Genetic Aspects of Allergic Rhinoconjunctivitis: A Review. J Otol Rhinol 4:6. doi:10.4172/2324-8785.1000258 |
Abstract
Allergic rhinoconjunctivitis (ARC) is a very common clinical entitiy effecting 20-30% of the population, with multiple allergies accompanying the situation as high as 54%. Being a type I hypersensitivity reaction to allergens, the symptoms of rhinitis and conjunctivitis mostly overlap, sharing common etiopathogenic properties. Allergic rhinitis is an inflammation of the nasal mucosa caused by an immune reaction mediated by immunoglobulin (Ig) E antibodies. Clinically, it is characterized by sneezing, rhinorrhea, nasal obstruction, and itching of the nasal membranes, pharynx, and soft palate. Allergic rhinitis is the most prominent of allergic diseases and is accompanied by bronchial asthma and especially ocular symptoms.
