Advances in Psoriasis Management: From Conventional Therapies to Biologics

Psoriasis is a chronic inflammatory skin disease affecting millions worldwide, characterized by red, scaly plaques and associated comorbidities. This article reviews traditional and modern management strategies, highlighting the evolution from topical and systemic therapies to biologic agents targeting specific immune pathways. Recent research has improved understanding of the immunopathogenesis of psoriasis, leading to targeted treatments that offer better efficacy and safety profiles. Additionally, advancements in phototherapy and small molecule inhibitors present promising options for refractory cases. This review explores the mechanisms, benefits, limitations, and future directions in psoriasis treatment.