Archives of Medical Biotechnology

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CRISPR Technology — A Transformative Tool in Modern Biomedical Science

CRISPR technology has emerged as one of the most revolutionary tools in biomedical research, offering unmatched precision and efficiency in genome editing. Originating from the adaptive immune system of bacteria, CRISPR-Cas systems have been repurposed to target, cut, and modify specific DNA sequences in living organisms. The ease of design, low cost, and high specificity have rapidly accelerated its application across medicine, agriculture, and biotechnology. In human health, CRISPR holds significant promise for treating genetic disorders, developing targeted cancer therapies, and improving infectious disease management. Despite its transformative potential, ethical concerns and risks related to offtarget effects and germline editing highlight the need for regulated and responsible use. This article discusses the fundamentals of CRISPR technology, its applications in medicine, and the challenges associated with clinical translation.

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