Evaluation of Metabolisable Energy Indices Following Experimental Salinomycin Toxicosis in Sheep

Evaluation of Metabolisable Energy Indices Following Experimental Salinomycin Toxicosis in Sheep

Salinomycin is an ionophore with antimicrobial properties. It is a dietary additive used as a growth promoter for ruminants and as a coccidiostat in chickens. However, overdosage or misuse situations can lead to a series of toxic syndromes. There are some reports with respect to the poisoning of animals with this agent used in high concentration in feed by mistake. This experiment was conducted to investigate the effect of salinomycin on variables related to energy metabolism such as glucose, β-hydroxybutyrate (BHB), non-esteritified fatty acid (NEFA), lactate, lipids (cholesterol and triglyceride) and lipoproteins (HDL, LDL and VLDL) in sheep.