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Journal of Veterinary Science & Medical Diagnosis ISSN: 2325-9590

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Research Article, J Vet Sci Med Diagn Vol: 2 Issue: 3

Evaluation of Metabolisable Energy Indices Following Experimental Salinomycin Toxicosis in Sheep

Hamid Rajaian1, Saeed Nazifi2*, Safoora Hashemi1, Ali Hajimohammadi2, Elham Mohsenifard2 and Maryam Ansari-Lari3
1Department of Basic Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
2Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
3Department of Food Hygiene and Public Health, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Corresponding author : Dr. S Nazifi
Professor of Veterinary Clinical Pathology, Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz, P.O. Box: 1731-71345, Iran
Tel: +98-711-2286940; Fax: +98-711-2286950
E-mail: [email protected]
Received: June 23, 2013 Accepted: September 24, 2013 Published: September 27, 2013
Citation: Rajaian H, Nazifi S, Hashemi S, Hajimohammadi A, Mohsenifard E, et al. (2013) Evaluation of Metabolisable Energy Indices Following Experimental Salinomycin Toxicosis in Sheep. J Vet Sci Med Diagn 2:3. doi:10.4172/2325-9590.1000118

Abstract

Evaluation of Metabolisable Energy Indices Following Experimental Salinomycin Toxicosis in Sheep

Salinomycin is an ionophore with antimicrobial properties. It is a dietary additive used as a growth promoter for ruminants and as a coccidiostat in chickens. However, overdosage or misuse situations can lead to a series of toxic syndromes. There are some reports with respect to the poisoning of animals with this agent used in high concentration in feed by mistake. This experiment was conducted to investigate the effect of salinomycin on variables related to energy metabolism such as glucose, β-hydroxybutyrate (BHB), non-esteritified fatty acid (NEFA), lactate, lipids (cholesterol and triglyceride) and lipoproteins (HDL, LDL and VLDL) in sheep.

Keywords: Salinomycin toxicosis; Sheep; Glucose; β-hydroxybutyrate; Non esteritified fatty acid; Lactate; Lipids; Lipoproteins

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