Journal of Sleep Disorders: Treatment and CareISSN: 2325-9639

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Improved Sleep Quality in Patients Affected by Nocturnal Frontal Lobe Epilepsy (NFLE) Treated with Lacosamide: A Two Cases Report

Nocturnal Frontal Lobe Epilepsy (NFLE) is a form of focal epilepsy with heterogeneous clinical presentation of morpheic seizures that tend to cluster overnight, with a good response to carbamazepine (CBZ). We report two cases of NFLE patients associated with sleep disorders, successfully treated with lacosamide 200 mg/day. We hypothesized that lacosamide, in relation to its multiple action mechanisms, can have positive effects not only on seizures control but also on sleep disorders associated with them.

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