Archives of Clinical Pathology

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Oncology Nursing and Cancer Care 2018 - Pediatric hyalinizing trabecular adenoma of thyroid: A rare presentation

Hyalinising trabecular tumor (HTT) is an unusual and controversial neoplasm of the thyroid gland. The WHO classification of endocrine tumors describes it as a rare neoplasm of follicular cell origin with trabecular pattern of growth and marked intratrabecular hyalinization. It is mostly encountered in middle aged women. Pediatric cases are extremely rare. A 14 year male presented with swelling of the right lobe and isthmus of the thyroid. Partial thyroidectomy was performed. Grossly, an encapsulated well circumscribed nodule measuring 4 cms in diameter was seen in the right lobe. Microscopy showed features of hyalinizing trabecular adenoma (HTA). The histomorphological features of this entity overlap with papillary thyroid carcinoma, medullary thyroid carcinoma and paraganglioma to varying extent. Recognition of HTA in children can facilitate appropriate management.

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