Journal of Sleep Disorders: Treatment and CareISSN: 2325-9639

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Severe Obstructive Sleep Apnea in a Patient with Fragile X Syndrome

Fragile X Syndrome (FXS) is a common disorder associated with intellectual disability. It is a multi-systemic disorder (e.g. cardiac, neurological, growth, gastrointestinal, ocular and congenital). It is also associated with many psychiatric features (anxiety, autism spectrum disorder, attention and aggression). Sleep disorders tend to occur at a higher prevalence in patients with FXS (e.g. insomnia and obstructive sleep apnea). This case reports severe obstructive sleep apnea in a patient with FXS that was treated successfully with PAP therapy and lead to the improvement of several medical and psychiatric symptoms.

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